Hydroquinone: how safe is it ???? Hydroquinone is a very good medicine for pigmentation, if it is used judicially as instructed by the Dermatologist. it should not be used for more than 2 to 3 weeks continuously as it might cause major skin problems like ochronosis and thinning of skin . so when a doctor prescribes you any medicine follow the instructions properly. If you have ochronosis you should consult your skin specialist If you want to do online consultation with us you can WhatsApp on 836