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    Glibenclamide - Wikipedia

    Glibenclamide, also known as glyburide, is an antidiabetic medication used to treat type 2 diabetes. It is recommended that it be taken together with diet and exercise. It may be used with other antidiabetic medication. It is not recommended for use by itself in type 1 diabetes. It is taken by mouth. Common side effects … 展开

    Glibenclamide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.
    It is not as good as either 展开

    Glibenclamide may be not recommended in those with G6PD deficiency, as it may cause acute hemolysis.
    Pregnancy and breastfeeding
    It is generally not recommended during pregnancy but can be used during breastfeeding 展开

    It was developed in 1966 in a cooperative study between Boehringer Mannheim (now part of Roche) and Hoechst (now part of Sanofi-Aventis). 展开

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    Frequently reported side effects include: nausea, heartburn, weight gain, and bloating. The medication is also a major cause of medication-induced 展开

    The medication, a sulfonylurea, works by binding to and inhibiting the ATP-sensitive potassium channels (KATP) inhibitory regulatory subunit sulfonylurea receptor 1 (SUR1) in 展开

    Brand names
    Glibenclamide is available as a generic medication, is manufactured by many pharmaceutical companies and is sold under many brand names … 展开

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  4. Glyburide: Uses, Interactions, Mechanism of Action

    Glyburide is a drug that stimulates insulin secretion by closing ATP-sensitive potassium channels on pancreatic beta cells. It is used to treat adults with type 2 diabetes mellitus alone or in combination with metformin, …

  5. Glibenclamide - an overview | ScienceDirect Topics

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  10. Glibenclamide - an overview | ScienceDirect Topics

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    格列波脲的分子式:C18H26N2O4S ,密度:1.3g/cm3 ,原料药为格列本脲Glibenclamide,是一种白色晶体粉末,不溶于水,微溶于乙醇、丙酮、氯仿。. 与2型糖尿病患者的乳酸性酸中毒和低血糖相关。. 格列波脲的口服吸收快, …