Telomerase - Wikipedia
Telomerase, also called terminal transferase, [1] is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of …
Telomerase: Definition, Function, Structure and Cancer - Biology …
2017年7月25日 · Telomerase is an enzyme found inside our cells, which may be related to the aging process. It adds short, repetitive “caps” to our DNA strands. These caps are called …
Telomerase: structure, functions, and activity regulation
Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes and stem and …
Biochemistry, Telomere And Telomerase - StatPearls - NCBI Bookshelf
2022年12月11日 · Telomerase is a ribonucleoprotein structure comprising a functional RNA component and a catalytic reverse transcriptase component. The RNA component houses a …
Telomeres and telomerase: three decades of progress
2019年2月13日 · Three decades ago, the classic view was that telomeres protected the natural ends of linear chromosomes and that telomerase was a specific telomere-terminal transferase …
Telomerase | Description, Function, & Facts | Britannica
telomerase, enzyme that influences cell life span by adding organic compounds known as nucleotides to telomeres, segments of DNA located at the ends of chromosomes. Telomeres …
Telomeres - Structure, Function, and Regulation - PMC
In mammals, maintenance of the linear chromosome ends (or telomeres) involves faithful replication of genetic materials and protection against DNA damage signals, to ensure …
Regulation of human telomerase in homeostasis and disease
2020年4月2日 · Telomerase is a ribonucleoprotein complex, the catalytic core of which includes the telomerase reverse transcriptase (TERT) and the non-coding human telomerase RNA …
Composition and Function of Telomerase—A Polymerase …
Telomerase, as a primary mechanism for telomere maintenance, is also conserved in plants. Analogous to mammals, telomerase activity is suppressed in terminally differentiated tissues, …
Structures of telomerase at several steps of telomere repeat …
2021年5月12日 · Telomerase La-related protein p65 remodels several regions of TER, bridging the 5′ and 3′ ends and the conserved pseudoknot to facilitate assembly of the TERT–TER …