Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels. In sickle cell disease, red blood cells are misshaped, typically ...
Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH
2024年8月20日 · However, in sickle cell disease, the body has trouble keeping up with the rate that the cells are being destroyed. This can lead to a low number of red blood cells, called anemia. The resulting anemia can cause a person to be easily tired with less energy. Normal red cells and sickled red cells.
Sickle Cell Disease - Treatment - NHLBI, NIH
2024年9月30日 · View fact sheet. Crizanlizumab-tmca is approved for adults and children ages 16 years and older who have sickle cell disease. The medicine is given through an intravenous (IV) line in the vein once a month. The medicine helps prevent blood cells from sticking to blood vessel walls and blocking blood flow.
Sickle Cell Disease - Diagnosis - NHLBI, NIH
2024年9月9日 · Prenatal screening. Healthcare providers can also diagnose sickle cell disease before a baby is born. This can be done in two ways. The first uses a sample of amniotic fluid (the liquid in the sac surrounding a growing embryo). The second uses a sample taken from the placenta (the organ that attaches the umbilical cord to the womb).
Sickle Cell Disease: Milestones in Research and Clinical Progress ...
Overview. Learn about the history of sickle cell disease in the United States, from its discovery in 1910 to the NHLBI legacy of research that has advanced the understanding of sickle cell disease, improved clinical progress, and paved the way for widely available cures. Print Length:
Sickle Cell Disease - Symptoms - NHLBI, NIH
2024年8月20日 · Serious pain linked with sickle cell disease often requires treatment in a clinic or hospital. Fatigue (extreme tiredness), shortness of breath, dizziness, and irregular heartbeat. These are symptoms of serious anemia. Life-threatening anemia can be caused by conditions such as a splenic sequestration crisis crisis or an aplastic crisis .
How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
2024年8月22日 · It filters your blood and destroys old blood cells. In people who have sickle cell disease, red blood cells may get trapped in the spleen. This makes the spleen quickly grow larger than normal. Serious anemia can occur when red blood cells get trapped in the spleen. A large spleen may also cause pain in the left side of the belly.
Sickle Cell Disease Research - NHLBI, NIH
2024年8月23日 · The Sickle Cell Disease and Cardiovascular Risk — Red Cell Exchange (SCD–CARRE) trial is testing monthly automated exchange transfusions as a strategy to reduce serious complications of sickle cell disease, improve symptoms, and prevent hospitalization and death. Exchange transfusions remove a person’s blood and replace it with red blood ...
Sickle Cell Disease Fact Sheet - NHLBI, NIH
Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD. Print Length: 1 page. Publication Date:
Sickle cell disease seems to affect cognitive function in adults
March 29, 2019. Researchers funded by NHLBI found that adults with sickle cell disease have worse performance in several cognitive tests than their healthy siblings. The disadvantage remained the same even for the patients treated with hydroxyurea. According to the researchers, the study, published in the journal Neuropsychological ...