RA Pathophysiology • Johns Hopkins Arthritis Center
Rheumatoid arthritis is best characterized as an immune mediated inflammatory disease (IMID). Within a framework that recognizes both immunological activation and inflammatory pathways, we can begin to evaluate the multiple components of disease initiation and propagation.
Rheumatoid arthritis - Symptoms and causes - Mayo Clinic
2023年1月25日 · Rheumatoid arthritis can cause pain, swelling and deformity. As the tissue that lines your joints (synovial membrane) becomes inflamed and thickened, fluid builds up and joints erode and degrade. Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints.
Rheumatoid Arthritis (RA) - Rheumatoid Arthritis (RA) - Merck …
2023年9月10日 · Rheumatoid Arthritis (RA) - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
Pathology Outlines - Rheumatoid arthritis
2024年8月8日 · Physical examination reveals symmetrical swelling of the metacarpophalangeal and proximal interphalangeal joints. Laboratory testing reveals a positive rheumatoid factor (RF). A synovial biopsy is performed. Which of the following histologic findings is most characteristic of rheumatoid arthritis?
Epidemiology, Pathophysiology, and Diagnosis of Rheumatoid Arthritis…
2014年5月31日 · Rheumatoid arthritis (RA) is one of the more common autoimmune disorders, affecting approximately 1% of the population worldwide. The exact cause of RA is not known; however, initiation of disease...
Rheumatoid arthritis – McMaster Pathophysiology Review
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammatory polyarthritis caused by chronic inflammation of the synovium (the membrane present in synovial joints that lines the joint capsules and produces synovial fluid).
Rheumatoid arthritis involves a complex interplay among genotype, environmental triggers, and chance.
Recent Advances in Understanding the Pathogenesis of Rheumatoid …
2021年11月4日 · In this review, the latest RA research findings are discussed to better understand the pathogenesis, and finally, treatment strategies for RA therapy are presented, including both conventional approaches and new methods that have been developed in recent years or are currently under investigation. 1. Introduction.
Rheumatoid Arthritis (RA): Practice Essentials, Background, Pathophysiology
2023年9月5日 · Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease of unknown etiology. It usually presents as bilateral symmetric polyarthritis (synovitis) that affects the hands and feet...
Rheumatoid arthritis - World Health Organization (WHO)
2023年6月28日 · Rheumatoid arthritis causes inflammation and pain in one or more joints. It can happen in most joints, but it’s most common in the small joints of the hands, wrists and feet. RA is chronic and may worsen over time without treatment. It can lead to severe damage to the joint and surrounding tissue.