Phytoestrogens and breast cancer prevention: What is the …
The use of phytoestrogens as a natural source of estrogen has been rapidly accepted by consumers for various remedial or preventive purposes, including breast cancer prevention. Phytoestrogens exhibit mixed weak estrogen agonist/antagonist properties and antioxidative activity. They may play a significant inhibitory role during the initiation and promotional phases …
Phytonutrients and outcomes following breast cancer: a …
2023年12月9日 · Phytoestrogen consumption and phytotherapy (herbal medicine, botanical medicine) use are prevalent following a breast cancer diagnosis for reasons that include preventing recurrence or metastasis and prolonging life (4, 5).Exposure to phytonutrients (bioactive phytochemicals, or plant-derived compounds) and their sources may be through …
Dietary phytoestrogens and breast cancer risk123
The incidence of invasive breast tumors in our study population was ≈300/100 000 women [≈86% of total breast tumors (0.86 × 280 × 100 000/80 215)], and the incidence of invasive breast cancer that was expected on the basis of Dutch cancer rates published in 1997 (weighted by the relevant age categories) was similar (ie, 285/100 000 women ...
Phytoestrogens and prevention of breast cancer: The ... - PubMed
2014年10月10日 · Abstract. Phytoestrogens have multiple actions within target cells, including the epigenome, which could be beneficial to the development and progression of breast cancer. In this brief review the action of phytoestrogens on oestrogen receptors, cell signalling pathways, regulation of the cell cycle, apoptosis, steroid synthesis and epigenetic ...
Phytoestrogens and the risk of breast cancer: a review of the ...
Epidemiological studies suggest that diets rich in phytoestrogens, particularly soy and unrefined grain products, may be associated with low risk of breast cancer. This review presents the studies published so far exploring a link between dietary phytoestrogens and breast cancer risk. Methods: A Medline search was conducted using the key words ...
Phytoestrogens and Breast Cancer Prevention: Possible …
2008年1月16日 · The effects of phytoestrogens on the growth and proliferation of tumor cells have also been evaluated in vivo, using animal models of breast cancer and breast cancer cell xenografts. Genistein and soy protein stimulated the growth of MCF7 breast cancer cell xenografts implanted in mice ( Allred et al. 2001 ; Hsieh et al. 1998 ).
Phytoestrogens for Cancer Prevention and Treatment - PMC
2020年11月27日 · This allows them to act as weak estrogenic factors and interfere with hormonal signaling. Several reports suggest that phytoestrogens may have a positive effect on the prevention of menopausal symptoms, type 2 diabetes, cardiovascular disease, obesity, and cancer. These health benefits are presumably linked to their anti-inflammatory, anti ...
about phytoestrogens and breast cancer. We review the available evidence regarding (1) the relationship between Implications of Phytoestrogen Intake for Breast Cancer 260 CA A Cancer Journal for Clinicians Dr. Duffyis Assistant Professor of Medicine, Brown University Medical School, Brown University, Providence, RI. Dr. Perez is Clinical ...
Exploring the Biological Activity and Mechanism of Xenoestrogens …
2021年8月16日 · The biological effects of phytoestrogens on breast cancer have also been linked to age and critical time points in a woman’s life . In premenopausal women, who are at high risk for early breast cancer, dietary isoflavone intake has been associated to increase breast cell cancer risk by promoting cancer cell growth.
Phyto-oestrogens and breast cancer chemoprevention
2004年3月18日 · Phytoestrogens are polyphenol compounds of plant origin that exhibit a structural similarity to the mammalian steroid hormone 17β-oestradiol. In Asian nations the staple consumption of phyto-oestrogen-rich foodstuffs correlates with a reduced incidence of breast cancer. Human dietary intervention trials have noted a direct relationship between phyto …