2024年4月19日 · The pathophysiology of portal vein thrombosis encompasses 1 or more features of Virchrow triad, which include reduced portal blood flow, a hypercoagulable state, or vascular endothelial injury. A confluence of splenic and superior mesenteric veins forms a portal vein, which carries blood from the spleen and small intestine to the liver.

The underlying causes of portal vein thrombosis (PVT) are frequently multifactorial and include malignancies, progressive chronic liver diseases, processes localized to the epigastrium and hepatobiliary system, and acquired as well as inherited thrombophilia.

Portal vein thrombosis (PVT) is the formation of a blood clot (thrombus) that narrows or blocks your portal vein. This vein carries blood to your liver from organs in your abdomen (belly). Clots can also develop in your portal vein’s branches (inside your liver) or the blood vessels that drain into your portal vein ( superior mesenteric vein ...

In this review, we analyze the physiopathological mechanisms of PVT development, together with the hemodynamic and functional alterations related to this condition. Moreover, we describe the principal factors most frequently involved in PVT development and the recent knowledge concerning diagnostic and therapeutic procedures.

Portal vein obstruction can result from one or several of the following 3 mechanisms: thrombosis, invasion by a malignant tumor (mainly hepatocellular carcinoma) and constriction within a malignant tumor (adenocarcinoma of the pancreas or bile ducts).

2022年2月2日 · Portal vein thrombosis (PVT) is a common complication among patients with cirrhosis. However, its pathophysiology is not well established and there are currently very few predictive factors, none of which are actually useful, from a clinical perspective.

Portal vein thrombosis (PVT) is defined as the appearance of a thrombus in the portal vein or its branches, with or without an extension to the superior mesenteric vein or the splenic vein (the so-called splanchnic territory) [1].

2024年7月9日 · This Review first provides a comprehensive overview of all aspects of PVT, namely the specifics of the portal venous system, the risk factors for PVT, the pathophysiology of portal hypertension in PVT, the interest in non-invasive tests, as well as therapeutic approaches including the effect of treating risk factors for PVT or cause of ...

2025年1月8日 · Portal vein thrombosis may be seen in a variety of clinical contexts, and when acute can be a life-threatening condition. It is a major cause of non-cirrhotic presinusoidal portal hypertension.

Portal vein thrombosis (PVT) is a vascular disease of the liver that occurs when a blood clot occurs in the hepatic portal vein, which can lead to increased pressure in the portal vein system and reduced blood supply to the liver. The mortality rate is approximately 1 in 10.