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  1. Diphenhydramine - Wikipedia

    • The drug is an ingredient in several products sold as sleep aids, either alone or in combination with other ingredients such as acetaminophen (paracetamol) in Tylenol PM and ibuprofen in Advil PM. Diphenhydramine can cause minor psychological dependence. [36] Diphenhydramine has also been used as an anxiolytic. [37]… 展开

    Overview

    Diphenhydramine (DPH) is an antihistamine and sedative first developed by George Rieveschl and put into commercial use … 展开

    History

    In 1943, diphenhydramine was discovered by chemist George Rieveschl and one of his students, Fred Huber, while they were conducting research into muscle relaxants at the University of Cincinnati. Huber first synthesized diph… 展开

    Medical uses

    Diphenhydramine is a first-generation antihistamine used to treat a number of conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. … 展开

     
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  4. Diphenhydramine - StatPearls - NCBI Bookshelf

    2023年7月10日 · The drug's time to peak, serum is 2 hours. Administration Diphenhydramine can be given by tablet, capsule, or solution by mouth; by intramuscular (IM) or intravenous (IV) injection; or topically.

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