2024年11月20日 · Bone-marrow-derived precursors enter the thymus in the medulla or around the corticomedullary junction (CMJ) and migrate to the cortex, where the CD4 − CD8 − double-negative (DN) thymocytes...

2024年9月5日 · ME-5 localized to the cortex and corticomedullary boundary, ME-15 extended from the corticomedullary boundary to the medulla, ME-9 was concentrated around TAL_2 cells in the medulla, and ME-16...

The corticomedullary junction is the boundary between the renal cortex and the renal medulla of the kidney. This junction is an important anatomical landmark as it delineates the transition between the outer, highly vascularized cortex and the inner, less vascularized medulla.

2024年6月1日 · Initially, early thymic progenitors (ETPs) take residence in the thymic cortex, where thymocytes begin to express their TCR and undergo positive selection. Subsequently, thymocytes transition to the thymic medulla, where they undergo negative selection.

2020年11月25日 · By analyzing genes with local spatial expression maxima, we observed a smooth transition from cortical to IMCD-PCs along the corticomedullary axis rather than sharp boundaries of gene expression.

2024年10月7日 · Bone marrow-originated T cell precursors enter the thymus through blood vessels in the corticomedullary junction and then migrate into the cortex for the subsequent development process. 1,2 At that time, they are termed double negative (DN) cells in the absence of CD4 and CD8 expression.

Figure 1 shows the optical image of three HE-stained sections of the cortex, corticomedullary transition, and medulla of the human kidney. Glomeruli, proximal and distal tubules, collecting ducts, and interstitial vessels were identified by optical microscopy.

Figure 1 shows the optical image of three HEstained sections of the cortex, corticomedullary transition, and medulla of the human kidney. Glomeruli, proximal and distal tubules, collecting ducts,...

Four weeks of MBG infusion triggered mild periglomerular and peritubular fibrosis in the cortex and the appearance of fibrotic scars in the corticomedullary junction of the kidney. MBG also significantly increased the protein levels and nuclear localization of the transcription factor Snail in the tubular epithelia.

2008年1月1日 · The corticomedullary junction (CMJ) and cortex may also contain adult renal stem cells, as shown by the presence of cells bearing the stem cell specific transcription factor Oct4 in the CMJ, cells bearing the stem cell marker CD133 in the cortex, and CD24/CD133 coexpressing cells in the glomerular parietal epithelium of the cortex [7–9].