Low vision originating in the cornea is the 4th leading cause of blindness globally (5.1%) according to the World Health Organization. Our laboratory’s main interest is the corneal epithelium, which is maintained by stem cells residing in the limbus, the area between the cornea and conjunctiva.

The Cornea Genetics Laboratory focuses on identifying and characterizing the molecular genetic basis of corneal dystrophies, and elucidating the normal and disease biology of corneal endothelial cells. The Laboratory employs an array of genetic analysis tools to identify causative mutations associated with inherited corneal disorders, and ...

Cornea Lab at R.P Centre. A new cornea laboratory has been started this year (2000). It is equipped with the latest state-of-art equipment used for examination of various corneal disorders. These include : Orbscan II; Humphrey Corneal Topography system; Non contact specular microscope; Slit Lamp with corneal endothelial counter; Ultrasonic ...

We develop and apply in vivo confocal microscopy and in situ multiphoton imaging techniques to assess the cellular responses to corneal injury, disease and refractive surgical procedures.

Pathology: Corneal endothelium (CE) forms a monolayer of hexagonal cells that is attached to its basement membrane, called Descemet’s membrane (DM) and is in direct contact with the aqueous humor.

The Cornea Genetics Laboratory is staffed by postdoctoral researchers, students and volunteers. Laboratory researchers originate from different parts of the world and represent both vision-specific and general cell biological disciplines.

Our lab seeks develop advanced experimental methods and micro-mechanical models to investigate the relationship between the collagen structure, mechanical properties, and physiologicall function of the cornea and sclera, and their alterations with age and disease.

Mootha Lab uses human genetics and genomics to understand the molecular basis of Fuchs' endothelial corneal dystrophy and develop novel therapeutic strategies.

The Corneal Innovation Lab is dedicated to pioneering novel therapies and innovations aimed at safeguarding and regenerating the cornea. Through cutting-edge research and interdisciplinary collaborations, our lab explores advanced techniques such as tissue engineering, biomaterials, and regenerative medicine to develop transformative strategies ...

The cornea is the principal refractive element in the eye; corneal transparency and shape determine its optical qualities. Corneal epithelial edema, stromal edema and shape anomalies can independently or collectively degrade visual performance in the form of increased light scatter and optical aberrations due to irregular astigmatism.