Circulating tumor cells: biology and clinical significance
2021年11月22日 · Abstract. Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and extravasate into and circulate in the blood. Understanding of the …
Circulating tumor cell - Wikipedia
A circulating tumor cell (CTC) is a cancer cell from a primary tumor that has shed into the blood of the circulatory system, or the lymph of the lymphatic system. [1] .
Circulating tumour cells for early detection of clinically relevant cancer
2023年6月2日 · Metastases are usually formed from cancer cells that spread to distant non-malignant tissues via the blood circulation, termed circulating tumour cells (CTCs).
Liquid biopsies: Understanding ctDNA and circulating tumor cells
2021年8月23日 · As cancer cells go through their life cycle, fragments of DNA can enter the bloodstream. This is known as circulating tumor DNA – or ctDNA, for short. ctDNA testing …
Circulating tumor cells: from new biological insights to clinical ...
2024年9月2日 · Recent advancements in technology have significantly enhanced our comprehension of the mechanisms behind the bloodborne spread of circulating tumor cells …
Detection of circulating tumor cells: opportunities and challenges
Circulating tumor cells (CTCs) are cells that shed from a primary tumor and travel through the bloodstream. Studying the functional and molecular characteristics of CTCs may provide in …
Circulating Tumor Cells: Strategies for Capture, Analyses, and ...
Circulating tumor cells (CTC) play a central role in tumor dissemination and metastases, which are ultimately responsible for most cancer deaths. Technologies that allow for identification …
Circulating Tumor Cells: A Review of Present Methods and the …
The measurement and characterization of circulating tumor cells (CTCs) hold promise for advancing personalized therapeutics. CTCs are the precursor to metastatic cancer and thus …
Circulating tumour cells: a broad perspective - PMC
2020年7月29日 · Circulating tumour cells (CTCs) constitute an exceedingly small fraction of cells relative to a background of 1 million white blood cells (WBCs) and 1 billion red blood cells …
Circulating tumor cell isolation for cancer diagnosis and prognosis
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor or metastasis loci and intravasate into the peripheral blood circulation system spontaneously or even possibly …
Circulating tumour cell clusters: isolation, biological significance ...
2024年9月9日 · Circulating tumour cells (CTCs) and CTC clusters are considered metastatic precursors due to their ability to seed distant metastasis. However, navigating the bloodstream …
Circulating tumor cells: biology and clinical significance
2021年11月22日 · Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and extravasate into and circulate in the blood. Understanding of the metastatic …
Circulating tumor cells in cancer patients: developments and …
2020年1月24日 · Circulating tumor cells (CTCs) are shed into the bloodstream from either primary or metastatic tumors during an intermediate stage of metastasis. In recent years, …
The biology of circulating tumor cells | Oncogene - Nature
2015年6月8日 · Circulating tumor cells (CTCs) are cells that are shed from primary tumors and metastatic deposits into the blood stream. CTCs bear a tremendous potential to improve our …
Circulating Tumor Cells: Origin, Role, Current Applications, and …
2024年9月20日 · Circulating Tumor Cells: Origin, Role, Current Applications, and Future Perspectives for Personalized Medicine. by. Maria Cristina Rapanotti. 1,*, Tonia Cenci. 1, …
Circulating Tumor Cells: Come Together, Right Now, Over …
2019年1月9日 · Circulating tumor cells (CTC) are the source of metastases, but only an infinitesimal fraction of them eventually succeed in colonizing a distant organ. New results …
Circulating tumor cell-blood cell crosstalk: Biology and clinical ...
2022年8月30日 · Circulating tumor cells (CTCs) are the seeds of distant metastasis, and the number of CTCs detected in the blood of cancer patients is associated with a worse prognosis. …
Advanced single-cell and spatial analysis with high-multiplex ...
2024年11月16日 · Background Metastatic prostate cancer is a highly heterogeneous and dynamic disease and practicable tools for patient stratification and resistance monitoring are urgently …
Electrothermal therapy for the in vivo elimination of circulating tumor ...
2024年11月11日 · The elimination of circulating tumor cells (CTCs) has recently emerged as a reliable route to inhibit metastasis of cancer. Despite some progress of photodynamic therapy …
Biology, vulnerabilities and clinical applications of circulating ...
2022年12月9日 · Among the most intriguing liquid analytes are circulating tumour cells (CTCs), which are shed from primary and/or metastatic tumours into the bloodstream to eventually …
Circulating tumor DNA - Wikipedia
Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion …
The tissue and circulating cell-free DNA-derived genetic …
2024年11月14日 · Colorectal adenomas (CRAs) represent precancerous lesions that precede the development of colorectal cancer (CRC). Regular monitoring of CRAs can hinder the …
Functional analysis of circulating tumour cells: the KEY to
2022年4月28日 · A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire. Int J Oncol. …
Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …