Chondrocyte - Wikipedia
Chondrocytes (/ ˈkɒndrəsaɪt, - droʊ -/, [1] from Greek χόνδρος (chondros) 'cartilage' and κύτος (kytos) 'cell') are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans.
Histology, Chondrocytes - StatPearls - NCBI Bookshelf
2023年4月17日 · The cartilage is solely composed of cells known as chondrocytes. Chondrocytes maintain the extracellular matrix (ECM) and produce the cartilage matrix. Surrounded by collagenous fibers, chondrocytes release substances to make cartilage strong yet flexible.
Chondrocytes: anatomy and function - Kenhub
2024年3月19日 · Chondrocytes produce collagen and the extracellular matrix. They are found in the avascular tissue known as cartilage . The extracellular matrix that is produced by the chondrocytes is important in the maintenance of cartilaginous tissue.
Chondrocytes - What Are Chondrocytes?, Structure, Location, …
Chondrocytes are the cells making up the cartilage. They are pivotal to synthesize cartilage matrix and sustain the extracellular matrix. It primarily comprises the proteoglycans and collagen.
Chondrocyte - an overview | ScienceDirect Topics
Chondrocytes are highly specialized cells that differentiate from clusters of mesenchymal cells during skeletal embryogenesis. The chondrocyte synthesizes and secretes the components of the extracellular matrix, primarily proteoglycans and type II collagen.
The Role of Chondrocyte Morphology and Volume in Controlling …
Articular chondrocytes in healthy adult articular cartilage are typically quiescent, highly differentiated cells which, through a balance between anabolism and catabolism of matrix constituents, maintain a resilient extracellular matrix (ECM).
Frontiers | Molecular Mechanisms of Chondrocyte Proliferation …
2021年5月27日 · Chondrocytes are the only cell type (accounting for 1%) in cartilage tissue and secrete growth factors and enzymes to regulate extracellular matrix (ECM) synthesis. They further embed themselves in ECM to form cartilage (Jiang and Tuan, 2014).
A high-resolution route map reveals distinct stages of chondrocyte ...
2022年4月27日 · In this study, we demonstrate a time-lapse atlas of chondrocyte dedifferentiation to provide molecular details and informative biomarkers associated with clinical chondrocyte evaluation.
Chondrocyte - an overview | ScienceDirect Topics
Chondrocytes are the constituent cells of cartilage, and through their function in endochondral ossification—the process by which most vertebrate bones are formed—play a central role in determining the rate of bone growth (Hunziker, 1994).
Chondrocyte Homeostasis and Differentiation: Transcriptional …
Chondrocytes live in an avascular environment in healthy cartilage with a low oxygen supply. Although chondrocytes are adapted to anaerobic conditions, many of their metabolic functions are oxygen-dependent, and most cartilage oxygen is supplied by the synovial fluid.