Microglia - Wikipedia
Microglia are a type of glial cell located throughout the brain and spinal cord of the central nervous system (CNS). [1] Microglia account for about 10–15% of cells found within the brain. [2] As …
Microglia in neurodegenerative diseases: mechanism and …
2023年9月22日 · Here we comprehensively review the biology of microglia and the roles of microglia in neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, …
Microglia: Structure, function and origin - Kenhub
2024年3月21日 · Microglia are a type of glial cell which are essential for the defense mechanisms in the central nervous system (CNS). Microglia share structural and functional similarities with …
Microglia | Description & Function | Britannica
2024年11月6日 · Microglia, type of neuronal support cell (neuroglia) in the central nervous system of invertebrates and vertebrates that mediates immune responses by acting as macrophages, …
Microglial signatures and their role in health and disease
2018年9月11日 · Microglia are the primary innate immune cells in the CNS. In the healthy brain, they exhibit a unique molecular homeostatic ‘signature’, consisting of a specific transcriptional …
What Do Microglia Really Do in Healthy Adult Brain? - PMC
In this review, we explore the neurobiology of microglia in the healthy adult brain and discuss the evidence for microglia influencing the cognitive processes of learning and memory, directly or …
Microglia Biology: One Century of Evolving Concepts - Cell Press
Microglia were first recognized as a distinct cell population in the CNS one century ago. For a long time, they were primarily considered to be phagocytes responsible for removing debris during …
Microglia and macrophages in brain homeostasis and disease
2017年11月20日 · This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal …
Microglia: The Brain’s First Responders - PMC
Microglia are the permanent resident immune cells of the brain and spinal cord, sharing many similarities with macrophages—the cells that destroy pathogens—outside the central nervous …
The ins and outs of microglial cells in brain health and disease
Microglia depletion has provided insight into the ability of the brain to repopulate microglia from different cell resources, underscoring their essential functions. These studies also exposed the …
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