Kinase - Wikipedia
In biochemistry, a kinase (/ ˈ k aɪ n eɪ s, ˈ k ɪ n eɪ s,-eɪ z /) [2] is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.
Kinase | Definition, Biology, & Function | Britannica
Kinase, an enzyme that adds phosphate groups to other molecules. A large number of kinases exist, the human genome alone containing hundreds of kinase-encoding genes. Included among kinase targets for phosphorylation are proteins, lipids, and nucleic acids.
Protein Kinases: Function, Substrates, and Implication in Diseases
In this Special Issue “Protein Kinases: Function, Substrates, and Implication in Diseases”, we collected seven review papers and five original research articles, focused on new findings, recent advances and future development in the protein kinase field.
Protein kinase - Wikipedia
A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which modify lipids, carbohydrates, or other molecules.
An Introduction to Kinases - The Daily Scientist
2023年12月1日 · What is a Kinase and How Does it Work in the Cell. Kinases are enzymes that help regulate cells of all living organisms by controlling signal transduction pathways. In essence, they act as a catalyst to “switch on/off” various cellular functions including metabolism and growth.
Ten things you should know about protein kinases: IUPHAR …
Protein and lipid kinases represent an important target class for treating human disorders. This review focus on ‘the 10 things you should know about protein kinases and their inhibitors', including a short introduction on the history of protein kinases and their inhibitors and ending with a perspective on kinase drug discovery.
Protein Kinases - an overview | ScienceDirect Topics
Protein kinase is a family of enzymes that catalyzes the transfer of a phosphate group from ATP to a protein or peptide substrate.
The secret life of kinases: functions beyond catalysis
2011年10月28日 · Here, we discuss such kinase independent functions of protein and lipid kinases focussing on kinases that play a role in the regulation of cell proliferation, differentiation, apoptosis, and motility.
Protein kinases: drug targets for immunological disorders
2023年5月15日 · This Review describes their clinical application, with a focus on Janus kinase inhibitors, and how they inform mechanisms of disease and have evolved to improve efficacy and safety.
Protein Kinases Overview: Definition, Types, Function, Activation ...
Protein kinases (PKs), belonging to the kinase family, are a kind of phosphotransferases responsible for the transfer of the γ-phosphate from ATP to the specific amino acid residues of the substrate proteins.
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