Cystine - Wikipedia
Cystine is the oxidized derivative of the amino acid cysteine and has the formula (SCH 2 CH (NH 2)CO 2 H) 2. It is a white solid that is poorly soluble in water. As a residue in proteins, cystine serves two functions: a site of redox reactions and a mechanical linkage that allows proteins to retain their three-dimensional structure. [1]
Cystine | Cysteine Metabolism, Protein Synthesis, Antioxidant
Cystine, a crystalline, sulfur-containing amino acid that is formed from two molecules of the amino acid cysteine. Cystine can be converted to cysteine by reduction (in this case, the addition of hydrogen). Discovered in 1810, cystine was not recognized as …
Cystine Stones (Cystinuria): Causes, Symptoms & Treatment
Cystine stones are a type of kidney stone made from a chemical called cystine. People with a rare genetic condition called cystinuria get cystine stones. The goal of treatment is to prevent cystine stones from forming.
Cysteine - Wikipedia
Cysteine (symbol Cys or C; [5] / ˈsɪstɪiːn /) [6] is a semiessential [7] proteinogenic amino acid with the formula HOOC−CH (−NH2)−CH2−SH. The thiol side chain in cysteine often participates in enzymatic reactions as a nucleophile. Cysteine is chiral, but both D and L …
Cystine | C6H12N2O4S2 | CID 67678 - PubChem
Cystine is a chemical substance which naturally occurs as a deposit in the urine, and can form a calculus (hard mineral formation) when deposited in the kidney. The compound produced when two cysteine molecules linked by a disulfide (S-S) bond.
Cystine Stones | National Kidney Foundation
2014年8月12日 · Cystine stones are kidney stones caused by the inherited disorder cystinuria. They can cause pain, blood in urine, and may require treatment like increased water intake, dietary changes, or surgery.
Cystine - an overview | ScienceDirect Topics
Cystine is a type of amino acid that is formed by the oxidation of two molecules of cysteine, which are amino acids containing sulfur. It plays a crucial role in stabilizing the structure of proteins by forming disulfide bonds between cysteine residues. You might find these chapters and articles relevant to this topic.
Cysteine Oxidation in Proteins: Structure, Biophysics, and …
We present an analysis of the role of cysteine reactivity as a regulatory factor in proteins, emphasizing the interplay between electrostatics and redox potential as key determinants of the resulting oxidation state.
Molecular basis for redox control by the human cystine ... - Nature
2021年12月8日 · Structural comparisons reveal an allosteric mechanism for ligand discrimination, supported by molecular dynamics and cell-based assays, establishing a mechanism for cystine transport in human...
The cystine/cysteine cycle: a redox cycle regulating susceptibility ...
2007年9月10日 · Our results show that system x c− protects against oxidative stress not by elevating intracellular GSH levels, but rather creates a reducing extracellular environment by driving a highly efficient...