Caspase - Wikipedia
Caspases are synthesised as inactive zymogens (pro-caspases) that are only activated following an appropriate stimulus. This post-translational level of control allows rapid and tight regulation of the enzyme.
Caspases in cell death, inflammation and disease - PMC
Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight into the molecular mechanisms that control caspase activation has emerged in recent years.
Caspases in Cell Death, Inflammation, and Disease - PubMed
2019年6月18日 · Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight into the molecular mechanisms that control caspase activation has emerged in recent years.
Caspases and their substrates - PMC - PubMed Central …
Caspases are a family of cysteine proteases whose functions are inextricably linked with the process of programmed cell death, or apoptosis, in all metazoans, including C. elegans, Drosophila, mouse and humans. 1, 2, 3 The enzymes predominantly cleave their substrates on the C-terminal side of aspartate, 4, 5 less frequently after glutamate and ...
Caspases in Cell Death, Inflammation, and Gasdermin …
Caspases are a family of conserved cysteine proteases that play key roles in programmed cell death and inflammation. In multicellular organisms, caspases are activated via macromolecular signaling complexes that bring inactive procaspases together ...
Caspases in Cell Death, Inflammation, and Disease - Cell …
Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation responses. A wealth of foundational insight into the molecular mechanisms that control caspase activation has emerged in recent years.
Caspases and their substrates | Cell Death & Differentiation
2017年5月12日 · Human caspases are a family of 12 fate-determining cysteine proteases that are best known for driving cell death, either apoptosis or pyroptosis.