Pathology Outlines - Histology
2023年8月31日 · Urothelium is exclusive to the conducting passages of the urinary system (renal pelvis, ureter, bladder, upper urethra and prostatic ducts) (Am J Physiol Renal Physiol 2009;297:F1477) > 90% of bladder carcinomas arise from the urothelium, mostly from the posterior wall of the bladder (Nat Cell Biol 2014;16:982)
Bladder & urothelial tract - Pathology Outlines
F-N: features to report, grossing & frozen section female urethral carcinoma fibroepithelial polyp flat hyperplasia flat lesions with atypia of unknown significance flat lesions with reactive changes follicular cystitis grading-bladder granulomatous cystitis hemorrhagic cystitis histology inflammatory myofibroblastic tumor interstitial cystitis ...
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2023年11月28日 · Urinary bladder, neck, biopsy: Inverted urothelial papilloma (see comment) Comment: The bladder lesion shows an invaginating polypoid proliferation of anastomosing cords and trabeculae with peripheral palisading of cells. There is central streaming of urothelial cells. No exophytic components are noted.
Pathology Outlines - Schistosomiasis (bilharziasis)
2022年2月3日 · Pathophysiology. After penetration of skin or mucous membranes, schistosomulae migrate through the lungs to portal venous system and mature into adults. About 6 weeks later, adult worms migrate to bladder venules (Nat Rev Dis Primers 2018;4:13) Females lay eggs that reach the bladder wall, penetrate bladder mucosa and excrete into urine.
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2021年4月6日 · NMP22 BladderChek test is an FDA approved qualitative assay for surveillance and detection of bladder cancer (50% sensitivity and 87% specificity) (Curr Opin Urol 2019;29:203) Bladder tumor antigen (BTA): antigen produced by cancerous cells
Pathology Outlines - Interstitial cystitis
2023年6月26日 · A cystoscopy was performed and showed reddened mucosal areas with small vessels radiating towards a central scar, which were biopsied. No mass or lesion suspicious for malignancy was seen on cystoscopy and urine cytology was negative. Bladder biopsies showed the histology above. What is the most likely diagnosis? Bladder stones Infectious cystitis
Pathology Outlines - Squamous metaplasia
2022年7月14日 · 22 year old man with leukoplakia of the urinary bladder (BMJ Case Rep 2018;2018:bcr2018227019) 34 year old woman presenting with bladder mulberry-like fibroepithelial polyp with calcification and squamous cell metaplasia mimicking bladder carcinoma (J Int Med Res 2020;48:300060519896911)
Pathology Outlines - Nephrogenic metaplasia
5 天之前 · Board review style answer #2. C. PAX8, Napsin A, NKX3.1 Nephrogenic metaplasia is commonly positive for PAX8 and Napsin A and less commonly for HNF1 beta and GATA3. NKX3.1 is expressed almost exclusively in prostatic adenocarcinoma. Both nephrogenic metaplasia and prostatic adenocarcinoma express AMACR and AE1/3.
Papillary urothelial neoplasm of low malignant potential
2022年9月6日 · This diagnostic category is justified because the recurrence and progression rates of papillary urothelial neoplasm of low malignant potential (PUNLMP) are expected to be higher than urothelial papilloma and lower than low grade noninvasive urothelial carcinoma. Recurrence rate: 18 - 20% (Am J Clin Pathol 2010;133:788, Diagn Pathol 2015;10:3)
Pathology Outlines - Anatomy & histology-male urethra
2023年7月20日 · Divided into prostatic, membranous and penile urethra (Ross: Histology - A Text and Atlas, 7th Edition, 2015, Gartner: Color Textbook of Histology, 3rd Edition, 2006) Prostatic urethra Extends from the bladder neck through the prostate gland (3 - 4 cm) Lined by urothelium Ejaculatory ducts enter at the posterior wall