Sickle Cell Disease (SCD): Types, Symptoms & Causes - Cleveland Clinic
2023年8月3日 · Sickle cell disease (SCD) is the most common inherited blood disorder that affects your red blood cells. In SCD, a protein called hemoglobin, located within red blood cells, is abnormal. Hemoglobin is important. It’s the molecule that carries oxygen in your blood and throughout your body.
What Is Sickle Cell Trait? | Sickle Cell Disease (SCD) | CDC
2024年5月15日 · People with sickle cell trait (SCT) inherit one sickle cell gene and one normal gene. People with SCT usually do not have any of the symptoms of sickle cell disease (SCD), but they can pass the trait on to their children.
Sickle cell anemia - Symptoms & causes - Mayo Clinic
2022年12月22日 · In sickle cell anemia, some red blood cells are shaped like sickles or crescent moons. These sickle cells also become rigid and sticky, which can slow or block blood flow. The current approach to treatment is to relieve pain and help prevent complications of the disease.
Sickle cell disease - Wikipedia
Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2]
Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow causing lifelong health problems.
Diagnosis of sickle cell disorders - UpToDate
2022年10月4日 · INTRODUCTION. Sickle cell disease (SCD) is an inherited group of disorders characterized by the presence of hemoglobin S (Hb S), either from homozygosity for the sickle mutation (Hb SS) or compound heterozygosity with another beta globin variant (eg, sickle-beta thalassemia, Hb SC disease).
Sickle cell disease - MedlinePlus
Sickle cell disease is the most common inherited blood disorder in the United States, affecting an estimated 100,000 Americans. The disease is estimated to occur in 1 in 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans.
Sickle Cell Anemia - StatPearls - NCBI Bookshelf - National …
2023年9月4日 · Sickle cell anemia is characterized by two major components: Hemolysis and vaso-occlusive crises (VOC). The defect in the beta-globin gene makes the sickle hemoglobin (HbS) molecule susceptible to converting into rigid, elongated polymers in a deoxygenated state.
Sickle Cell Disease - Sickle Cell Disease - The Merck Manuals
Sickle cell disease is an inherited genetic abnormality of hemoglobin (the oxygen-carrying protein found in red blood cells) characterized by sickle (crescent)-shaped red blood cells and chronic anemia caused by excessive destruction of the abnormal red blood cells. People have anemia and sometimes jaundice.
Sickle Cell Disease (SCD) | Sickle Cell Disease (SCD) | CDC
About. Read about types of sickle cell disease, as well as treatment and diagnosis. Learn More. For professionals. Sickle Cell Information for Healthcare Providers. Read this page for additional information for healthcare providers about sickle cell disease. Scientific Articles about Sickle Cell …