The primitive streak and cellular principles of building an amniote ...
2021年12月3日 · The primitive streak, a transient embryonic structure, marks bilateral symmetry in mammalian and avian embryos and helps confer anterior-posterior and dorsal-ventral spatial information to early differentiating cells during gastrulation.
The enigmatic primitive streak: prevailing notions and challenges ...
The primitive streak, a key structure in this process, provides unambiguous physical evidence of bilateral symmetry in the developing organism. During gastrulation, the streak extends through the embryonic midline, creating the anterior-posterior (A-P) body axis, and transforming primitive ectoderm (“epiblast”) into mesoderm and endoderm.
Embryonic Period (Weeks 3-8) - Wicha Lab
2000年1月6日 · Primitive Streak. The primitive streak is a linear band of thickened epiblast that first appears at the caudal end of the embryo and grows cranially. At the cranial end its cells proliferate to form the primitive knot (primitive node).
Induction and patterning of the primitive streak, an organizing center ...
2004年1月28日 · The primitive streak is the organizing center for amniote gastrulation. It defines the future embryonic midline and serves as a conduit of cell migration for germ layer formation. The migration patterns of endodermal and mesodermal precursors through the streak have been studied in great detail.
Primitive Streak - Cellular Development, Function & Anatomy
The primitive streak is a grooved structure that forms on day 15 of human development, along the caudal midline of the bilaminar embryonic disc and is the first visible sign of gastrulation. At the cranial end of the primitive streak, an expansion marks the location of the primitive node.
Primitive Streak - an overview | ScienceDirect Topics
The primitive streak is a transient inductive tissue that produces many important signaling molecules, including Wnt3, BMP4, and Nodal, and is also the point at which the naïve cells of the epiblast undergo epithelial to mesenchymal transition (EMT), emerging as either mesoderm or …
A developmental landscape of 3D-cultured human pre …
2019年12月12日 · These 3D embryos mimic developmental landmarks and 3D architectures in vivo, including the embryonic disc, amnion, basement membrane, primary and primate unique secondary yolk sac, formation of...
Molecular architecture of lineage allocation and tissue organization …
2019年8月7日 · Of note, the primitive streak cells at E6.5–E7.0 stages were separated from E7.5 primitive streak, which suggests the primitive streak is temporally heterogeneous at early and late...
Deconstructing and reconstructing the mouse and human early embryo - Nature
2018年7月23日 · In polarized EBs, aggregates of ESCs, known as EBs, undergo a process of symmetry breaking, specify a region of mesoderm, and form a primitive streak-like domain.
Embryology, Gastrulation - StatPearls - NCBI Bookshelf
2023年4月23日 · Primitive Streak. The initiation of the primitive streak is based upon a system of signaling pathways working to both positively and negatively regulate downstream expression. The combination of TGFB, Wnt, Nodal, and BMPs is important in primitive streak development.
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