Polycaprolactone (PCL) is a synthetic, semi-crystalline, biodegradable polyester with a melting point of about 60 °C and a glass transition temperature of about −60 °C. [2][3] The most common use of polycaprolactone is in the production of speciality polyurethanes.

Polycaprolactone is a semicrystalline linear polyester produced by ring-opening polymerisation of epsilon-caprolactone, which is commonly derived from fossil carbon. It has a much lower glass-transition temperature ( T g = − 60 °C) than other biodegradable polymers, which assists its biodegradability despite its high degree of crystallinity ...

2017年8月15日 · Polycaprolactone (PCL) is one of the earliest, commercially available, synthetic polymers characterized by a large set of biodegradation and mechanical properties that can be finely controlled by regulating the local environmental driving forces (ie, microorganisms, enzymes, hydrolysis).

2021年12月2日 · Overview - Polycaprolactone FDA engaged ECRI to perform a comprehensive literature search and systematic review to identify the current state of knowledge with regard to medical device material...

Polycaprolactone (PCL) is a semi crystalline hydrophobic biodegradable polyester which finds major applications as a drug delivery agent because of its cost efficiency, high toughness and biocompatibility.

Polycaprolactone (PCL) is a synthetic, semi-crystalline, biodegradable polyester with a melting point of about 60 degC and a glass transition temperature of about -60 degC. The most common use of polycaprolactone is in the production of speciality polyurethanes.

The non‐HA bioresorbable polycaprolactone (PCL)‐based filler with collagen‐stimulating properties has a proven safety profile, but rare potential complications such as nodules and granuloma can occur.

Poly ε-caprolactone (PCL) is a well-known synthetic aliphatic polyester universally used for many applications, including biomedical and environmental ones. Unlike poly lactic acid (PLA), PCL has no chiral atoms, and it is impossible to play with the stereochemistry to modify its properties.

This paper illustrates this with the example of polycaprolactone (PCL), a polymer synthesized in the early 1930s, and one of its most recent applications, a PCL-based collagen stimulator, a filler used in esthetics.

Polycaprolactone is a α,ω-dihydroxy functional polymer. Polycaprolactone may find use as an extrusion aid, die lubricant, mold release, pigment and filler dispersion aid and polyester segments in urethanes and block polyesters.