Phosphatidylinositol - Wikipedia
Phosphatidylinositol (PI), also known as inositol phospholipid, is a lipid composed of a phosphate group, two fatty acid chains, and one inositol molecule. It belongs to the class of phosphatidylglycerides and is typically found as a minor component on the cytosolic side of eukaryotic cell membranes.
Phosphoinositides as membrane organizers - Nature Reviews ...
2022年5月19日 · Phosphoinositides are signalling lipids derived from phosphatidylinositol, a ubiquitous phospholipid in the cytoplasmic leaflet of eukaryotic membranes.
Phosphatidylinositol - an overview | ScienceDirect Topics
Phosphatidylinositol refers to a molecule that plays multiple roles in biology, including modulating the function of membrane proteins. It is characterized by the presence of inositol in its headgroup and can undergo phosphorylation on the sugar hydroxyls.
Phosphoinositides: multipurpose cellular lipids with emerging ...
2019年2月11日 · Phosphorylated phosphatidylinositol lipids, or phosphoinositides, critically regulate diverse cellular processes, including signalling transduction, cytoskeletal reorganisation, membrane dynamics...
Phosphatidylinositol - an overview | ScienceDirect Topics
Phosphatidylinositol is the parent lipid for the synthesis of seven phosphorylated inositol lipids and each of them play specific roles in numerous processes including receptor-mediated signalling, actin cytoskeleton dynamics and membrane trafficking.
Phosphatidylinositol and Related Phosphoinositides - LIPID MAPS
2024年8月28日 · Phosphatidylinositol 4-phosphate is the precursor for the 4,5-bisphosphate, but it binds to a protein on the cytoskeleton of the cell and has its own characteristic functions. It is the most widely distributed of the phosphoinositides, and as well as the Golgi and the plasma membrane, it is present in late endosomes, lysosomes, secretory ...
Phosphatidylinositol - an overview | ScienceDirect Topics
Phosphatidylinositol (PI) is a lipid that is formed in the ER by the CDP-dependent PI exchange protein that catalyzes the attachment of inositol phosphate onto diacylglycerol (see Chapter 4; Sandelius and Morré, 1987). Inositol lipids are enriched in the cytosolic leaflets of membranes.