Pericytes Don’t Go With the Flow—They Change It - ALZFORUM
2017年2月13日 · Optogenetics can nevertheless be used to delineate mechanisms of pericyte contractility, which will help design better investigations of normal pericyte physiology. It also …
Human Blood-Brain Barrier Model Blames Pericytes for CAA
2020年6月15日 · Steven Greenberg Massachusetts General Hospital; Posted: 15 Jun 2020 This is a very elegant study, both technically in establishing a model of blood-brain barrier from …
Finally, a Dye to Visualize Pericyte Function - ALZFORUM
2017年5月23日 · This is a remarkable find for pericyte research because of its specificity and ease of application to any mouse model during live imaging. It is also extremely fortuitous that …
Tunneling Nanotubes—How Pericytes Control Blood Flow
2020年8月19日 · A tunneling nanotube (above dotted line) surrounded by basement membrane (green) connects the cell body of a proximal pericyte (red) to the process of a distal pericyte on …
Smooth Muscle Cells, Not Pericytes, Control Brain Blood Flow
2015年6月27日 · The authors, however, define a "pericyte" as a cell on a capillary that lacks smooth-muscle actin (a contractile protein) in processes around the vessel (for background …
Pericyte degeneration leads to neurovascular uncoupling and …
2017年2月13日 · Optogenetics can nevertheless be used to delineate mechanisms of pericyte contractility, which will help design better investigations of normal pericyte physiology. It also …
Interpericyte tunnelling nanotubes regulate neurovascular …
2020年8月19日 · Brain pericyte physiology is an emerging field that underlines how our understanding of brain cerebrovascular function, despite great progress, is limited. The field is …
Neural metabolic imbalance induced by MOF dysfunction triggers …
2020年6月29日 · Definition of pericyte markers has improved with the availability of single-cell transcriptomic datasets (Vanlandewijck et al. 2018), and the authors add to this body of …
Loss of Pericytes Wreaks Havoc in Mouse Brain | ALZFORUM
2018年2月10日 · “A pathogenic role of fibrinogen appears to be validated and extended in pericyte-deficient mice tested in this study,” said Katerina Akassoglou, University of California, …
Aβ Acts Through Pericytes to Throttle Brain Blood Flow
2019年6月22日 · The width (red bar) of a rat cortical capillary (left) shrinks in the vicinity of a pericyte (white arrowheads) after addition of Aβ (right). [Courtesy of Nortley et al., …