大约 45.9万 条结果
在新选项卡中打开链接
  1. Osteoclasts are bone-resorbing cells that are derived from hematopoietic precursor cells and require macrophage-colony stimulating factor and receptor activator of nuclear factor-κB ligand (RANKL) for their survival, proliferation, differentiation, and activation.
    Author: Jin Hee Park, Na Kyung Lee, Soo Young Lee
    Publish Year: 2017

    Current Understanding of RANK Signaling in Osteoclast ... - PubM…

    pubmed.ncbi.nlm.nih.gov/29047262/
    pubmed.ncbi.nlm.nih.gov/29047262/
    这是否有帮助?
  2. 其他用户还问了以下问题
    Does RANKL regulate osteoclast formation and function?
    Initial in vitro studies implicated RANKL in regulating osteoclast formation and function (33, 73), immune cell survival and activation such as dendritic cell (DC) survival and activation (78 – 80), and T-cell activation (81, 82).

    Osteoclasts: New Insights | Bone Research - Nature

    nature.com
    What is the difference between osteoclasts and osteoblasts?
    Osteoclasts and osteoblasts are the bone resorbing cells and bone-forming cells, respectively. Whereas multinucleated bone resorbing osteoclasts differentiate from mononuclear cells of the monocyte/macrophage lineage (7), osteoblasts are derived from mesenchymal stem cells (MSC) (8).

    Osteoclasts: New Insights | Bone Research - Nature

    nature.com
    Is rank essential for osteoclast and lymph node development?
    Dougall W.C., Glaccum M., Charrier K., Rohrbach K., Brasel K., De Smedt T., Daro E., Smith J., Tometsko M.E., Maliszewski C.R., et al. RANK is essential for osteoclast and lymph node development. Genes Dev. 1999;13:2412–2424. [ PMC free article] [ PubMed] [ Google Scholar]

    Current Understanding of RANK Signaling in Osteoclast Differentiation

    ncbi.nlm.nih.gov
    How does RANKL interact with osteoclast progenitors?
    RANKL binds to RANK expressed by osteoclast progenitors, resulting in the activation of signaling cascades including the mitogen-activated protein kinase (MAPK) and NF-κB pathways via the adaptor protein tumor necrosis factor receptor‐associated factor 6 (TRAF6) and the kinase TGF-β-activated kinase-1 (TAK1) [1, 2, 3] (Fig. 1).

    RANKL as the master regulator of osteoclast differentiation

    link.springer.com
    Where do osteoclasts come from?
    Osteoclasts are bone-resorbing multinucleated cells that originate from hematopoietic precursors that are formed in the bone marrow ( Asagiri and Takayanagi, 2007; Boyle et al., 2003; Karsenty and Wagner, 2002; Teitelbaum, 2000 ).

    Current Understanding of RANK Signaling in Osteoclast Differentiation

    ncbi.nlm.nih.gov
    What is the role of osteoclasts in osteoporosis?
    Osteoclasts are the exclusive bone-resorbing cells that have a central role in bone homeostasis as well as pathological bone resorption seen in osteoporosis, bone cancer and autoimmune arthritis [1, 2, 3].

    RANKL as the master regulator of osteoclast differentiation

    link.springer.com
    反馈
  3. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682248

    Current Understanding of RANK Signaling in Osteoclast …

  4. PubMed
    https://pubmed.ncbi.nlm.nih.gov/29047262

    Current Understanding of RANK Signaling in Osteoclast ... - PubMed

  6. Nature
    https://www.nature.com/articles/s12276-024-01157-7

    Unraveling the intricacies of osteoclast differentiation and …

    标记:
    Rank Osteoclast
    Rank Receptor
    Wishbone formation
  7. Nature
    https://www.nature.com/articles/s41413-018-0040-9

    RANKL-RANK signaling regulates osteoblast differentiation and …

    标记:
    Rankl Osteoporosis
    Rankl Osteocyte
    Rankl Rank Signaling in Osteoclast
  8. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413418

    Functions of RANKL/RANK/OPG in bone modeling and remodeling

    标记:
    Rankl Osteoporosis
    Rankl Rank Opg Signaling
    Rankl and Opg

  9. Osteoclasts and RANK的图片

    bing.com/images
    查看所有图像
  10. Inflammation and Regeneration
    https://inflammregen.biomedcentral.com…

    RANKL biology: bone metabolism, the immune system, …

    2020年2月7日 · Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts. Because abnormalities in RANKL, its signaling …

    标记:
    Rank Receptor
    Rankl Osteoporosis
    Rankl Osteocyte
    Receptor Activator
  11. Nature
    https://www.nature.com/articles/boneres20133

    Osteoclasts: New Insights | Bone Research - Nature

    标记:
    Rank Osteoclast
    Feng Xu, Steven L. Teitelbaum
    Publish Year:2013
  12. Springer
    https://link.springer.com/article/10.1007/s00774-020-01191-1

    RANKL as the master regulator of osteoclast differentiation

    标记:
    Publish Year:2021
    Hiroshi Takayanagi
    [email protected]
  13. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441501

    New Insights Into Osteoclast Biology - PMC - National Center for ...

    标记:
    Publish Year:2021
    Presidential Memorial Certificate
    New Insights Into Osteoclast
  14. PubMed
    https://pubmed.ncbi.nlm.nih.gov/33079279

    Osteoclast differentiation by RANKL and OPG signaling pathways

    标记:
    Publish Year:2021
    Rankl and Opg
    Receptor Activator
  16. 某些结果已被删除