NFKB1 - Wikipedia
NFKB1 - Wikipedia. Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene. [5] This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein.
NFKB1 Gene - GeneCards | NFKB1 Protein | NFKB1 Antibody
2024年10月2日 · NFKB1 (Nuclear Factor Kappa B Subunit 1) is a Protein Coding gene. Diseases associated with NFKB1 include Immunodeficiency, Common Variable, 12, With Autoimmunity and Common Variable Immunodeficiency. Among its related pathways are Toll Like Receptor 7/8 (TLR7/8) Cascade and TNFR1 Pathway.
NFKB1: a suppressor of inflammation, ageing and cancer
The importance of Nfkb1 function can be seen in mouse models, where Nfkb1(-/-) mice display increased inflammation and susceptibility to certain forms of DNA damage, leading to cancer, and a rapid ageing phenotype.
NF-κB - Wikipedia
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival.
NF-κB signaling in inflammation | Signal Transduction and
2017年7月14日 · Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors, which regulates a large array of genes involved in different processes of the immune and inflammatory...
NFKB1 nuclear factor kappa B subunit 1 [ (human)] - National …
High NFKB1 expression is associated with inflammatory uveal melanoma. NFKB1 rs28362491 polymorphism was significantly associated with the risk of head and neck carcinoma, especially with nasopharyngeal carcinoma.
NF-κB: At the Borders of Autoimmunity and Inflammation
2021年8月9日 · Loss-of-function of NFKB1 are the most common monogenic cause of common variable immunodeficiency in Europe associated with lymphadenopathy, splenomegaly and with age, autoimmunity and cancer .
NF-κB subunits direct kinetically distinct transcriptional cascades in ...
2023年7月31日 · The nuclear factor kappa B (NF-κB) family of transcription factors orchestrates signal-induced gene expression in diverse cell types. Cellular responses to NF-κB activation are regulated...
NFKB1 gene information - The Human Protein Atlas
General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene …
Deletion of NFKB1 enhances canonical NF-κB signaling and …
2019年7月29日 · NFKB1 deletion resulted in increased collagen deposition, increase macrophage recruitment, and increased presence of myofibroblasts.