The ins and outs of MHC class II-mediated antigen processing and ...
In this Review, we describe our current knowledge of the mechanisms of uptake and processing of antigens, the intracellular formation of peptide–MHC class II complexes, the intracellular …
Pathways of Antigen Processing - PMC - PubMed Central (PMC)
Conversion of antigens from pathogens or transformed cells into MHC-I and MHC-II-bound peptides is critical for mounting protective T cell responses, and similar processing of self …
A guide to antigen processing and presentation - Nature
2022年4月13日 · The MHC-II presentation pathway exploits physico-chemical means to tag proteins for degradation. The protease-rich compartments of the endocytic pathway are …
The ins and outs of MHC class II-mediated antigen processing and ...
2015年2月27日 · In this Review, we describe our current knowledge of the mechanisms of uptake and processing of antigens, the intracellular formation of peptide–MHC class II complexes, the …
MHC Class I, Class II, Antigen Processing, And Presentation
2022年5月23日 · The breaking down of antigens into peptides takes 1-3 hours to transverse the endocytic pathway and appear at the cell surface in the form of a peptide-class II MHC …
Major histocompatibility complex: Antigen processing and …
2013年7月18日 · Pathway by which extracellular antigens are processed and presented by HLA class II molecules. Extracellular proteins are taken into the cell by phagocytosis and are then …
Towards a systems understanding of MHC class I and MHC class II …
2011年11月11日 · Here, we discuss how the MHC class II antigen presentation pathway differs from the MHC class I pathway and thus presents protein fragments that are generated at …
Antigen Processing and Presentation | British Society for
MHC class II molecules bind to peptides that are derived from proteins degraded in the endocytic pathway. MHC class II complexes consists of α- and β-chains that are assembled in the ER …
Present Yourself! By MHC Class I and MHC Class II Molecules
2016年9月7日 · Since the discovery of MHC molecules, it has taken 40 years to arrive at a coherent picture of how MHC class I and MHC class II molecules really work. This is a story of …
MHC class II molecules on the move for successful antigen presentation
Major histocompatibility complex class II molecules (MHC II) are expressed by immune cells like B cells, dendritic cells (DCs), and monocytes/macrophages and designed to stably bind and …
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