The liver plays a key role in lipid metabolism. Depending on species it is, more or less, the hub of fatty acid synthesis and lipid circulation through lipoprotein synthesis.

2023年7月17日 · Information on the anatomy of the liver can be found here. In this article, we will consider the role of the liver in the metabolism of lipids, and we will discuss the clinical relevance of lipid metabolism in relevant disease states.

2019年7月21日 · This chapter discusses the interplay between lipid metabolism and chronic liver diseases focusing on NAFLD, alcoholic liver disease, hepatitis C, hepatitis B, cholestatic liver disease, and cirrhosis.

The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or indirectly contribute to NAFLD, especially fatty acid accumulation, ...

2019年9月25日 · Under healthy conditions, the liver regulates lipid metabolism to meet systemic energy needs in the fed and fasted states. The processes of fatty acid uptake, fatty acid synthesis and the...

2023年9月13日 · Lipid metabolism in the liver ranges from uptake of chylomicron-derived lipids and fatty acids arising from adipose tissue lipolysis, among other sources, to de novo lipogenesis,...

Liver lipid metabolism and its modulation are involved in many pathologic conditions, such as obesity, non-alcoholic fatty liver disease, diabetes mellitus, atherosclerosis and cardiovascular disease.

2016年6月30日 · Many liver diseases are accompanied by disorders in lipid metabolism, with the latter often involving the clinical condition of these patients. This chapter summarizes current understanding of hepatic lipid metabolism, including cholesterol and phospholipid metabolism, and associated factors.

By interacting with the intestinal tract and adipose tissue, the liver plays a key role in various aspects of lipid metabolism. Increasing activation of transcription factors, such as carbohydrate responsive element binding protein (ChREBP), sterol response element binding protein-1c (SREBP-1c), or forkhead box 01 (Fox01), may contribute to ...

2008年6月28日 · Lipid metabolism involves several pathways that are at least in part, inter-dependent and ‘cross-regulated’. There are therefore different possible approaches to review this topic to get an overview. The focus of the present discussion will be …