Laminin - Wikipedia
Laminins are heterotrimeric proteins with a high molecular mass (~400 to ~900 kDa) and possess three different chains (α, β, and γ) encoded by five, four, and three paralogous genes in humans, respectively. The laminin molecules are named according to their chain composition, e.g. laminin-511 contains α5, β1, and γ1 chains. [3] .
Laminin: Evidence of Divine Creation? - Snopes.com
断言: The cross-like shape of the laminin molecule is evidence of God's hand in the creation of the human form.
· 已被 snopes.com 证实13.5: Laminins - Biology LibreTexts
2022年12月30日 · Laminins are a family of secreted glycoproteins that are found in many ECM formations, and like fibronectin, bind to cells via integrin receptors. The laminin protein is composed of three subunits (α, β, γ) arranged in a cruciform shape. There are multiple isoforms of each subunit yielding the variety (15) of laminin proteins catalogued to date.
Laminin - an overview | ScienceDirect Topics
Laminin is a family of trimetric proteins containing α, β, and γ subunits with only certain subunits found in mammals and is a key component of basal lamina, a layer of ECM found in many tissues including the brain and blood vessels in the CNS (Nirwane and Yao, 2018).
Structural biology of laminins - PubMed
2019年9月13日 · Laminins are large cell-adhesive glycoproteins that are required for the formation and function of basement membranes in all animals. Structural studies by electron microscopy in the early 1980s revealed a cross-shaped molecule, which subsequently was shown to consist of three distinct polypeptide chains.
The laminin family - PMC
Laminins are large molecular weight glycoproteins constituted by the assembly of three disulfide-linked polypeptides, the α, β and γ chains. The human genome encodes 11 genetically distinct laminin chains.
Laminins: Roles and Utility in Wound Repair - PMC
Significance: Laminins are complex extracellular macromolecules that are major players in the control of a variety of core cell processes, including regulating rates of cell proliferation, differentiation, adhesion, and migration.