Reed–Sternberg cell - Wikipedia
Reed–Sternberg cells (also known as lacunar histiocytes for certain types) are distinctive, giant cells found with light microscopy in biopsies from individuals with Hodgkin lymphoma. They are usually derived from B lymphocytes, classically considered crippled germinal center B cells.
Reed-Sternberg Cell: Types and Diagnosis - ejmjih.com
2022年3月2日 · Reed-Sternberg cells (also known as lacunar histiocytes for certain types) are distinctive, giant cells found with light microscopy in biopsies from individuals with Hodgkin lymphoma. They are usually derived from B lymphocytes, classically considered crippled …
What Is Histiocytosis? - Cleveland Clinic
Histiocytosis refers to many rare blood disorders where white blood cells (histiocytes) build up in tissue. This includes conditions that range from mild and asymptomatic to potentially fatal. Everyone with histiocytosis has excess histiocytes in tissue that cause inflammation.
Glossary - Lymphoma Forum
A special type of Reed-Sternberg cells (RSCs) is the lacunar histiocyte, whose cytoplasm retracts when fixed in formalin, so the nuclei give the appearance of cells that lie with empty spaces (called lacunae) between them.
Reed-Sternberg cell - wikidoc
Reed-Sternberg cells (Lacunar Histiocytes for certain types) are distinctive giant cells found on light microscopy in biopsies from individuals with Hodgkin's lymphoma (aka Hodgkin's disease; a type of lymphoma), and certain other disorders. They are derived from B lymphocytes.
Shades of gray between large B-cell lymphomas and Hodgkin
2013年1月2日 · (a) Nodular sclerosis CHL (NSCHL) is characterized by cellular nodules surrounded by fibrous bands. (b) The infiltrate contains lacunar variants of Reed–Sternberg (RS) cells, with lobulated...
Hodgkin’s Lymphoma - SpringerLink
Reed-Sternberg (RS) cells are also known as lacunar histiocytes. The name is derived from two researchers, Dorothy Reed Mendenhall (1902) and Carl Sternberg (1898), who provided the first collaborative definitive microscopic description of Hodgkin’s “disease.”
Hodgkin lymphoma: Diagnostic criteria and pitfalls
2014年1月1日 · The histopathological and fine-needle aspiration (FNA) cytologic diagnosis of Hodgkin lymphoma (HL) is based on demonstration of pathognomonic mononucleated Hodgkin and bi- to multinucleated Reed-Sternberg (HRS) cells among reactive cellular components composed of lymphocytes, benign histiocytes, neutrophils and eosinophils.
Histiocytosis - The Lancet
2021年4月23日 · Histiocytoses are a clinically heterogeneous group of rare disorders (appendix p 2) with onset at any age, which remain challenging to diagnose and treat. However, recent discoveries of oncogenic mutations in the mitogen-activated protein (MAP) kinase cell-signalling pathway have revolutionised clinical management.
Revised classification of histiocytoses and neoplasms of the …
We propose herein a revision of the classification of histiocytoses based on histology, phenotype, molecular alterations, and clinical and imaging characteristics.