In biochemistry, isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. Isozymes usually have different kinetic parameters (e.g. different KM values), or are regulated differently.

2024年3月11日 · Isozymes, also known as isoenzymes, are enzymes that differ in amino acid sequence but catalyze the same chemical reaction· They usually have different kinetic parameters or are regulated differently. Isozymes are often the result of gene duplication, but can also arise from polyploidization or nucleic acid hybridization.

2023年5月29日 · Isozymes (also known as isoenzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. These enzymes usually display different kinetic parameters (i.e. different KM values), or different regulatory properties.

Isozymes are present in the serum and tissues of mammals, amphibians, birds, insects, plants and unicellular organisms. Isozymes of numerous dehydro­genases, and several oxidases, transaminases, phosphatases, transphosphorylases, proteolytic en­zymes, aldolases. 1.

The term “ isozyme ” was coined by Markert and Moller (1959) to loosely denote “…different molecular forms in which proteins may exist with the same enzymatic activity.” Over 100 isozyme systems have been described in animals, plants and protists. They do not represent a specific class of proteins.

The term isozyme is a general designation for multiple forms of a single enzyme. Isozymes will catalyze the same reaction, but they may differ in properties such as the pH or substrate concentration at which they best function.

Isozymes (also known as isoenzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. These enzymes usually display different kinetic parameters (i.e. different KM values), or different regulatory properties.

Isozymes are defined as multiple forms of enzymes occurring in the same organism and having similar or identical catalytic activities. They are usually demonstrated by the technique of zone electrophoresis followed by in situ histochemical staining for the specific activity. Most isozymes can be classified into primary and secondary types.

Isozymes are present in the serum and tissues of mammals, amphibians, birds, insects, plants and unicellular organisms. Examples: Isozymes of numerous dehydro­genases, and several oxidases, transaminases, phosphatases, transphosphorylases, proteolytic en­zymes, aldolases. Characteristics of Isozymes: 1.

any of several forms of an enzyme that all catalyze the same reaction but may differ in reaction rate, inhibition by various substances, electrophoretic mobility, or immunologic properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase, and creatine kinase, have clinically important isoenzymes.