Glycosylation - Wikipedia
Glycosylation is the reaction in which a carbohydrate (or 'glycan'), i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor) in …
Glycosylation: mechanisms, biological functions and clinical ...
2024年8月5日 · Glycosylation is crucial in regulating protein stability. Glycosylation can enhance the stability and solubility of proteins, thereby improving their half-life and drug properties in vivo.
Glycosylation in health and disease - Nature Reviews Nephrology
2019年3月11日 · Glycosylation is critical for physiological and pathological cellular functions; advances in analytical techniques have driven progression in the field of glycobiology over the …
Global view of human protein glycosylation pathways and functions - Nature
2020年10月21日 · Enzymatic glycosylation of proteins involves a complex metabolic network and different types of glycosylation pathways that orchestrate enormous amplification of the …
Protein glycosylation: Current Biology - Cell Press
2019年4月1日 · What is protein glycosylation? Protein glycosylation is the covalent attachment of single sugars or glycans, i.e., multi-sugar polysaccharides or complex oligosaccharides, to …
Cellular Organization of Glycosylation - Essentials of Glycobiology ...
This chapter provides an overview of glycosylation from the perspective of a single cell, taking into account the patterns of expression, topology, and other features of the biosynthetic and …
Glycosylation: mechanisms, biological functions and clinical ...
2024年8月5日 · Glycosylation is one of the most common PTMs, in which polysaccharides are transferred to specific amino acid residues in proteins by glycosyltransferases. A growing body …
Global view of human protein glycosylation pathways and functions
Glycosylation is the most abundant and diverse form of post-translational modification of proteins that is common to all eukaryotic cells. Enzymatic glycosylation of proteins involves a complex …
Glycosylation - an overview | ScienceDirect Topics
Glycosylation is defined as a common post-translational modification involving the addition and extension of carbohydrates on proteins and lipids. It plays a crucial role in various biological …
Understanding glycosylation: Regulation through the metabolic …
2023年10月1日 · Glycosylation is a highly dynamic, multi-layered post-translational modification. Metabolic flux through precursor pathways is vital for sustained glycan synthesis. Inflammation …