In simple terms, a liver glycogen sparing effect ensures that more liver glycogen is, therefore, available late in exercise, thereby maintaining plasma glucose availability and delivery to the muscle to meet the CHO oxidation rates necessary to sustain the required workload.

A simplified overview of glycogen metabolism at rest and during exercise. The sarcolemma separates the muscle cell interior from the interstitial fluid that surrounds the cell. At rest (left side), the consumption of carbohydrate stimulates the release of insulin from the pancreas.

"glycogen sparing" published on by Oxford University Press. The use of non-carbohydrates as a source of energy during exercise so that the depletion of muscle glycogen stores is delayed. If fat, for example, makes a greater contribution to an athlete's efforts during the initial stages of a race, more glycogen will be available for the later ...

Glycogen is currently not only considered an energy substrate but also a regulator of the signaling pathways that regulate exercise-induced adaptations. Thus, low or high CHO availabilities can result in both beneficial or negative results depending on the purpose.

2024年9月2日 · What is Glycogen Sparing? When you run, your body burns two primary fuel sources: glycogen (stored carbohydrates) and fat. Glycogen is the body’s preferred energy source for high-intensity efforts, while fat is a slower-burning fuel used during lower-intensity exercise.

Endurance training is associated with glycogen (Gly) sparing, generally attributed to less carbohydrate (CHO) oxidation. However, untrained individuals commit a greater fraction of CHO to lactate (La), accounting for a portion of the Gly "spared." We examined the effects of training (running 1 h/day …

Glycogen sparing in the liver and possibly muscle. Carbohydrate feedings during exercise “spare” liver glycogen (Jeukendrup et al. 1999), and Tsintzas and Williams (Tsintzas et al. 1998) discussed a potential muscle glycogen sparing effect.

2015年12月21日 · This review summarizes the current knowledge about the effects of glycogen availability on skeletal muscle adaptations for both endurance and resistance exercise. Furthermore, it describes the role of glycogen availability when both exercise modes are performed concurrently.

Euglycaemia and oxidation of blood glucose at high rates late in exercise and a decreased rate of muscle glycogen utilisation (i.e. glycogen 'sparing') have been proposed as possible mechanisms underlying the ergogenic effect of CHO ingestion.

2016年9月1日 · Therefore, liver glycogen sparing in an endurance-trained state may account partly for training-induced performance/capacity adaptations during prolonged (>90 min) exercise. Ingestion of carbohydrate at a relatively high rate (>1.5 g/min) can prevent liver glycogen depletion during moderate-intensity exercise independent of the type of ...