Gametocyte - Wikipedia
A gametocyte is a eukaryotic germ cell that divides by mitosis into other gametocytes or by meiosis into gametids during gametogenesis. Male gametocytes are called spermatocytes, and female gametocytes are called oocytes.
Revisiting gametocyte biology in malaria parasites - PMC
2019年4月9日 · Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology.
Gametocytogenesis in malaria parasite: commitment, …
Gametocytes are obligatory for parasite transmission from an infected human host to a female Anopheles mosquito. Shortly after ingestion by the mosquito, gametocytes in the blood meal undergo gametogenesis to produce male and female gametes. For male gametocytes, the genome is replicated three times and eight flagellated microgametes are produced.
Repurposing the mitotic machinery to drive cellular elongation …
2022年8月27日 · The sexual stage gametocytes of the malaria parasite, Plasmodium falciparum, adopt a falciform (crescent) shape driven by the assembly of a network of microtubules anchored to a cisternal inner...
Gametocytes: insights gained during a decade of molecular …
2008年9月26日 · Investigating whether the conversion to gametocytes during the transmission-free season is a constraint (by-product) of the cell cycle or an adaptation is a key question. Understanding how host immune responses regulate parasitaemia in chronic infections might help to explain patterns of gametocyte investment.
The Biology of Malaria Gametocytes - IntechOpen
2016年11月30日 · Gametocytes are sexual precursor cells of the malaria parasite that mediate the transmission of the parasite from its mammalian host to the Anopheles mosquito. Unlike the asexual blood stages, which are responsible for the clinical outcome of malaria, gametocytes cause no clinical manifestations.
Gametogenesis in Plasmodium : Delving Deeper to Connect the Dots
2022年6月15日 · The current review is focused on one of these aspects i.e., transmission control, by looking deeper into the event called gametogenesis. In the Plasmodium life cycle, gametocytes are the first life forms of the sexual phase. The transmission of the parasite and the disease is critically dependent on the number, viability and sex ratio of mature ...
Gametocytes: insights gained during a decade of molecular
In vertebrate hosts, malaria parasites produce specialized male and female sexual stages (gametocytes). Soon after being taken up by a mosquito, gametocytes rapidly produce gametes and, once mated, they infect their vector and can be transmitted to new hosts.
Gametocyte - an overview | ScienceDirect Topics
Gametocyte. In subject area: Medicine and Dentistry. Gametocytes undergo meiosis cell division, which is characterized by two cycles (meiosis I and meiosis II) that result in the formation of four daughter cells, or gametes, that contain only one copy of each chromosome (haploid cells).
Dissecting the role of PfAP2-G in malaria gametocytogenesis
2020年3月20日 · We find that PfAP2-G is a transcriptional activator of early gametocyte genes, and identify differences in PfAP2-G occupancy between gametocytes derived via next-cycle and same-cycle conversion.
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