Uncaria gambir, the gambier or gambir, is a species of plant in the genus Uncaria found in Southeast Asia, mainly Malaysia and Indonesia. Gambier extract is used or has been used as a catechu for chewing with areca and betel, for tanning and dyeing, and as herbal medicine.

Gambier or gambir is an extract derived from the leaves of Uncaria gambir, a climbing shrub native to tropical Southeast Asia. Gambier is produced in Indonesia and Malaysia where it was an important trade item into the late nineteenth century.

Uncaria Gambir possess health benefits. It is an Astringent and Styptic. The leaves and twigs of the plant are used to treat Diarrhea. The leaves and twigs are dried and crushed. It is used as Tea. It attacks the bacteria that causes Diarrhea in the colon.

Gambir extract at the dose of 80 mg/kg BW exhibited the highest efficacy in reducing TNF alpha level, lesion area and increasing prostaglandin E2 level compared to gambir extract at doses of 20 mg/kg BW, 400 mg/kg BW, negative control, and positive control.

Various studies have shown that extracts and compounds obtained from U. gambir have medical uses for their antioxidant, antibacterial, anti-helminthic, anticancer, antifungal, anti-inflammatory, anti-hyperglycemic, anti-hyperuricemic, anti-lipid peroxidation, antihyperlipidemic and …

Gambir is a trusted remedy for accelerating wound healing due to its antibacterial properties. It effectively fights and prevents bacterial infections, speeding up the blood clotting process [10,11]. Acne, Wrinkles, and Dark Spots: Gambir extract contributes to facial health and youthfulness with its anti-inflammatory and antioxidant properties.

Indonesian Gambier (U. gambir) is a large tropical vine with leaves typical of the genus, being opposite and about 10 cm (3.9 in) long. The South American U. tomentosa is called Uña de Gato. Uncaria sinensis is common in China.