Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans. [2] The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease's most dangerous form, falciparum malaria.

2023年8月8日 · Severe and fatal malaria is predominantly caused by Plasmodium falciparum. Its management and prognosis depend on the awareness of a possible diagnosis in travelers returning from endemic areas, early recognition, and timely effective treatment.

Infections caused by P. falciparum are the most likely to progress to severe, potentially fatal forms with central nervous system involvement (cerebral malaria), acute renal failure, severe anemia, or acute respiratory distress syndrome. Other species can also have severe manifestations.

2024年3月20日 · Plasmodium falciparum- infected erythrocytes, particularly those with mature trophozoites, adhere to the vascular endothelium of venular blood vessel walls and do not freely circulate in the blood.

2024年6月5日 · Malaria can be a severe, potentially fatal disease, especially when caused by Plasmodium falciparum. Ensure prompt diagnosis followed by immediate treatment. The treatment regimen depends on infecting plasmodium species, patient's clinical status, drug-resistance status, and previous use of antimalarials.

2024年12月11日 · P. falciparum is the deadliest malaria parasite and the most prevalent on the African continent. P. vivax is the dominant malaria parasite in most countries outside of sub-Saharan Africa. The other malaria species which can …

The three species associated with more severe cases are P. falciparum (which is responsible for the vast majority of malaria deaths), P. vivax, and P. knowlesi (a simian malaria that spills over into thousands of people a year). [13][14] P. ovale and P. malariae generally cause a milder form of malaria. [1][10] Malaria is typically diagnosed by ...

2023年2月9日 · Malaria is a disease caused by a parasite. The parasite is spread to humans through the bites of infected mosquitoes. People who have malaria usually feel very sick with a high fever and shaking chills. While the disease is uncommon in temperate climates, malaria is still common in tropical and subtropical countries.

2023年8月8日 · Malaria is a mosquito-borne disease caused by five protozoa: Plasmodium falciparum, P. vivax, P. malariae, P. ovale, and most recently implicated P.knowlesi. Infection with P. falciparum is being accounted for more than 90% of the world’s malaria mortality and therefore remains an important threat to public health on a global scale.

The fever and chills of malaria are associated with the rupture of erythrocytic-stage schizonts. In severe falciparum malaria, parasitized red cells may obstruct capillaries and postcapillary venules, leading to local hypoxia and the release of toxic cellular products.