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Definition of Drug-Induced Cognitive Impairment in the Elderly
2000年6月14日 · Neuroleptic malignant syndrome is characterized by delirium, fever, autonomic dysfunction, extrapyramidal syndrome, and recent history of antipsychotic use.
Positive Phase 3 Results for Antipsychotic in Schizophrenia
2024年1月12日 · The investigational antipsychotic KarXT is effective in reducing positive and negative symptoms of schizophrenia, with a favorable side-effect profile in the pivotal EMERGENT-2 trial.
Olanzapine Associated With Lower Rate of Extrapyramidal
Oct. 2, 2003 — Olanzapine was associated with the fewest patients with extrapyramidal symptoms (EPS) at six months compared with baseline, according to the results of a large prospective trial ...
'Impressive' New Data on Novel Schizophrenia Hopeful KarXT
2024年5月8日 · The primary endpoint was a change from baseline in the Positive and Negative Syndrome Scale (PANSS) total score at week 5. ... There were no between-group differences in measures of extrapyramidal ...
Levetiracetam for Managing Neurologic and Psychiatric Disorders
Levetiracetam has shown its beneficial effects in a patient with Meigs' syndrome ( Table 2). [ 62 , 63 ] Yardimci et al. [ 62 ] reported a case of a 64-year-old woman with Meigs' syndrome whose ...
FDA OKs First-in-Class Antipsychotic for Schizophrenia - Medscape
2024年9月27日 · The US Food and Drug Administration (FDA) has approved Cobenfy (Bristol Myers Squibb), a first-in-class antipsychotic approved for schizophrenia.The drug targets cholinergic receptors as opposed ...
Metoclopramide in the Treatment of Diabetic Gastroparesis
In 479 reports of metoclopramide-related extrapyramidal reactions in the UK from 1967–1982, 455 were for acute dystonias, 20 for parkinsonism and four for TD. [ 64 ] Acute Dystonic Reactions
FDA Approves Iloperidone for Bipolar Disorder - Medscape
2024年4月3日 · The incidence of akathisia and extrapyramidal symptoms was low in the treatment group, and the medication was well tolerated. The most common adverse events were tachycardia, dizziness, dry mouth ...
The pathophysiology of extrapyramidal side-effects of ... - Medscape
2025年1月17日 · The mechanisms responsible for the production of major extrapyramidal side-effects (parkinsonism, akathisia, acute dystonic reactions, chronic tardive dyskinesias) are reviewed in the light of the ...
Antipsychotic Polypharmacy With Risperidone and Olanzapine
2017年8月8日 · After 10 weeks, significant differences between the two groups were lacking for positive and negative syndrome scale (PANSS) scores, extrapyramidal symptoms, and other adverse effects.