Antigen Recognition by B-cell and T-cell Receptors ...
Membrane-bound immunoglobulin on the B-cell surface serves as the cell's receptor for antigen, and is known as the B-cell receptor (BCR). Immunoglobulin of the same antigen specificity is …
Immunology, Chapter 4: Antigen-Recognition by B-cell, and T ...
The function of the B-cell receptor is to recognize and bind antigen via the V regions exposed on the surface of the cell, thus transmitting a signal that activates the B cell, leading to clonal …
11.3B: Antigen-presenting Cells - B and T cells - Biology ...
Nov 23, 2024 · This recognition, which is central to the functioning of the adaptive immune response, results from the presence of highly specific receptors on the surfaces of B and T …
Defining and studying B cell and T cell receptor interactions
B- and T-cell receptors (BCRs, Antibodies, and TCRs, or AIRs, adaptive immune receptors) are the means by which the adaptive immune system recognizes foreign and self-antigens, …
Antigen recognition by T cells - Immunobiology - NCBI Bookshelf
Both types of T-cell receptor differ from the membrane-bound immunoglobulin that serves as the B-cell receptor: a T-cell receptor has only one antigen-binding site, whereas a B-cell receptor …
Antigen receptor structure and signaling pathways ...
The antigen receptors on B cells (the B-cell receptor or BCR) and T cells (the T-cell receptor or TCR) are multiprotein complexes made up of clonally variable antigen-binding chains—the …
Mechanical control of antigen detection and discrimination by ...
May 24, 2024 · The adaptive immune response is orchestrated by just two cell types, T cells and B cells. Both cells possess the remarkable ability to recognize virtually any antigen through …
Role of B-cell receptors for B-cell development and antigen ...
By specifically binding antigen through the BCR, B cells are activated and differentiate into plasma cells through extra-follicular differentiation (6) or start the T-cell-dependent germinal center …