Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production.

2017年9月26日 · As with virtually every treatment currently available, both anti-estrogen drugs and immunotherapies can cause side effects in patients.

Aromatase inhibitors are a class of medicines that work by blocking the enzyme aromatase, the enzyme that converts androgens into estrogen. Aromatase inhibitors are used in the treatment of breast cancer to reduce levels of circulating estrogen.

2025年1月25日 · Hormone therapy is only used for breast cancers that are found to have receptors for the naturally occurring hormones estrogen or progesterone. Hormone therapy for breast cancer is often used after surgery to reduce the risk that the cancer might return. Hormone therapy also may be used to shrink a cancer before surgery.

2021年8月12日 · Antiestrogen is a form of hormonal therapy that aims to slow or stop the growth of hormone-sensitive tumors. The therapy works in several ways. It can block the...

2016年12月16日 · The type of anti-estrogen therapy you go through depends on the stage of your cancer, whether you’ve experienced menopause, and other health considerations. Let’s break down the major types of anti-estrogen therapy for ER+, early-stage breast cancer patients.

2024年6月25日 · Hormone therapy for breast cancer treatment is different than menopausal hormone therapy (MHT). Hormone therapies used in breast cancer treatment act as “anti-hormone” or “anti-estrogen” therapies. They block hormone actions …

antiestrogen, any substance that blocks the synthesis or action of the hormone estrogen. Estrogen can be both a beneficial and a harmful hormone. It maintains skeletal strength by preventing the loss of bone and enhancing calcium retention.

A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and pregnancy). Antiestrogens may stop some cancer cells from growing and are used to prevent and treat breast cancer.

Antiestrogens are estrogen receptor antagonists at the hypothalamic level, increasing GnRH secretion, and at the pituitary level, increasing FSH and LH gonadotropins, by blocking the negative feedback of estrogens, generated mainly after aromatization of testosterone, thus stimulating spermatogenesis and steroidogenesis.6.