The Anterior-Posterior (AP) axis is the most ancient of the embryonic axes, and exists in most metazoans. Different animals use a wide variety of mechanisms to create this axis in the early embryo.

The establishment of the anterior–posterior (A–P) axis is a fundamental event during early development and marks the start of the process by which the basic body plan is laid down. This axial information determines where gastrulation, that generates and positions cells of the three-germ layers, occurs.

2025年2月9日 · The key signalling factors are Wnt family proteins for the anterior-posterior axis, Bmp family proteins for the dorsal-ventral axis and Nodal for the left-right axis. Cnidarians, the sister group to bilaterians, are characterized by one oral-aboral body axis, which exhibits a distinct biradiality of unknown molecular nature. ...

The anterior-posterior axis of the embryo is therefore specified by three sets of genes: those that define the anterior organizing center, those that define the posterior organizing center, and those that define the terminal boundary region.

2018年1月1日 · In the mouse, a specialized population of cells, the anterior visceral endoderm (AVE) undergoes a migration event critical for correct A–P pattern. In this review, we summarize our understanding of the generation of anterior pattern, focusing on the role of the AVE.

The anterior-posterior axis is critical for defining an organism's body layout, determining where limbs and organs will develop. This axis is established during early embryonic development through a series of genetic and molecular signals.

2023年1月9日 · Anterior-posterior axis formation regulated by the distal visceral endoderm (DVE) and anterior visceral endoderm (AVE) is essential for peri-implantation embryogenesis. However, the principles of the origin and specialization of DVE and AVE remain elusive.

The anterior-posterior axis is a fundamental concept in anatomy and plays a critical role in the orientation of an organism's body structures. It is defined by a line extending from the head, or anterior end, to the tail, or posterior end of the body.

In the mouse, a specialized population of cells, the anterior visceral endoderm (AVE) undergoes a migration event critical for correct A-P pattern. In this review, we summarize our understanding of the generation of anterior pattern, focusing on the role of the AVE.

The anterior-posterior axis provides a framework for establishing where neural tissue will form during neural induction. Specific signaling molecules released from structures like the notochord influence which cells become neural progenitors.