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    Adenosine A1 receptor - Wikipedia

    • The adenosine A1 receptor (A1AR) is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as endogenous ligand. 展开

    Biochemistry

    A1 receptors are implicated in sleep promotion by inhibiting wake-promoting cholinergic neurons in the
    The … 展开

    Signaling

    Activation of the adenosine A1 receptor by an agonist causes binding of Gi1/2/3 or Go protein. Binding of Gi1/2/3 causes an inhibition of adenylate cyclase and, therefore, a decrease in the cAMP concentration. A… 展开