Acetyltransferase - Wikipedia
An acetyltransferase (also referred to as a transacetylase) is a type of transferase enzyme that transfers an acetyl group, through a process called acetylation.
N-acetyltransferase - Wikipedia
N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. [1][2][3] They have wide specificity for aromatic amines, particularly serotonin, and can also …
Histone acetyltransferase - Wikipedia
Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε- N -acetyllysine. DNA is wrapped around histones, and, by transferring an acetyl group to the histones, genes can be turned on and off.
Histone acetyltransferases: challenges in targeting bi-substrate ...
2016年5月26日 · Histone acetyltransferases (HATs) are epigenetic enzymes that install acetyl groups onto lysine residues of cellular proteins such as histones, transcription factors, nuclear receptors, and enzymes.
Acetyltransferase Definition & Meaning - Merriam-Webster
The meaning of ACETYLTRANSFERASE is any of several enzymes that catalyze the transfer of acetyl groups —called also transacetylase.
The role of histone acetyltransferases in normal and malignant ...
Histone acetyltransferases (HATs), which are the enzymes responsible for histone and non-histone protein acetylation, contain p300/CBP, MYST, and GNAT family members. HATs are not only protein modifiers and epigenetic factors but also critical regulators of …
List of Lysine Acetyltransferases in Mammals - esbl.nhlbi.nih.gov
Below are the lysine acetyltransferases found in mammals. The information was culled and curated from several existing resources (click to open): Histome: The Histone Infobase, UniProtKB, NCBI, Rat Genome Database, Cell Signaling Technology, Drazic et al. 2016.
Histone Acetyltransferase Enzymes: From Biological Implications …
2019年11月28日 · The acetylation of lysine residues of histone and nonhistone proteins is a post-translational modification catalysed by the so-called histone acetyltransferases (HATs) that plays a crucial role in several biological settings.
Multifunctional acyltransferase HBO1: a key regulatory factor for ...
2024年11月14日 · HBO1, also known as KAT7 or MYST2, is a crucial histone acetyltransferase with diverse cellular functions. It typically forms complexes with protein subunits or cofactors such as MEAF6, ING4, or ING5, and JADE1/2/3 or BRPF1/2/3, where the BRPF or JADE proteins serve as the scaffold targeting histone H3 or H4, respectively. The histone acetylation …
Histone acetylation and the role of histone deacetylases in …
2020年8月13日 · Histone acetylation is co-regulated by two sets of enzymes - histone acetyltransferases (HATs) and histone deacetylases (HDACs). Deregulation of HDACs and histone acetylation is often associated with endometrial pathologies such as cancer, endometriosis, and infertility [7, 8, 9, 10].
- 某些结果已被删除