AH-7921 - Wikipedia
AH-7921 (Doxylam) is an opioid analgesic drug selective for the μ-opioid receptor, having around 90% the potency of morphine when administered orally. [2] [3] [4] It was discovered in the 1970s [5] by a team at Allen and Hanburys located in the United Kingdom. [6]
AH-7921: the list of new psychoactive opioids is expanded
2015年2月21日 · AH-7921 is a new, structurally atypical synthetic opioid analgesic that appears to be sold as a “research chemical” or “legal opioid” on the Internet since 2012.
AH-7921: A review of previously published reports - PMC
2018年6月1日 · AH-7921 is a synthetic opioid that was developed in the early 1970s. It has resulted in several fatal and nonfatal intoxications, despite not having approval from the US Food and Drug Administration. To date, AH-7921 is listed as a schedule I drug, and there have been no clinical trials exploring the safety of AH-7921.
AH-7921: the list of new psychoactive opioids is expanded
AH-7921 is a structurally unique synthetic opioid analgesic that has recently entered the drug arena in Europe, the USA, and Japan. Although it was synthesized and patented in the mid-1970s, it was first identified in a seized sample purchased via the Internet in July 2012 and formally brought to th ….
Non-fentanyl-derived synthetic opioids emerging during recent …
The AH-7921, a benzamide compound belonging to the U-compounds, developed by Allen and Hanburys Ltd. in the mid-1970s, has been very active in this group. Before the postulation of generic legislation by China for fentanyl-related substances in 2019 [ 6 ], the synthetic opioids sometimes appeared as the combination of FA and U-compounds [ 10 ].
AH-7921: A review of previously published reports - PubMed
2018年6月1日 · AH-7921 is a synthetic opioid that was developed in the early 1970s. It has resulted in several fatal and nonfatal intoxications, despite not having approval from the US Food and Drug Administration.
AH-7921: A new synthetic opioid of abuse - Wiley Online Library
2014年10月10日 · Since 2012, a new synthetic opioid named AH-7921 has become available within the recreational drug market 1. AH-7921, IUPAC name 3,4-dichloro-N-[[1-(dimethylamino)cyclohexyl]methyl]benzamide, is an N-substituted cyclohexylmethylbenzamide where the benzamide moiety is dichlorinated at positions 3 and 4 of the ring and the …
Metabolic characterization of AH-7921, a synthetic opioid …
AH-7921 (3,4-dichloro-N- [ (1-dimethylamino)cyclohexylmethyl]benzamide) is a new synthetic opioid and has led to multiple non-fatal and fatal intoxications. To comprehensively study AH-7921 metabolism, we assessed human liver microsome (HLM) metabolic stability, determined AH-7921’s metabolic profile after human hepatocytes incubation ...
AH-7921: the list of new psychoactive opioids is expanded
2015年8月10日 · AH-7921 is a structurally unique synthetic opioid analgesic that has recently entered the drug arena in Europe, the USA, and Japan.
AH-7921 - Wikiwand
AH-7921 (Doxylam) is an opioid analgesic drug selective for the μ-opioid receptor, having around 90% the potency of morphine when administered orally. It was discovered in the 1970s by a team at Allen and Hanburys located in the United Kingdom.