Acetazolamide: a second wind for a respiratory stimulant in the ...
2012年8月7日 · Acetazolamide, a non-specific carbonic anhydrase inhibitor, is one of the drugs employed in the ICU to reverse metabolic alkalosis. The drug is relatively safe, undesirable …
Acetazolamide-mediated decrease in strong ion difference …
2006年1月9日 · Introduction Metabolic alkalosis is a commonly encountered acid–base derangement in the intensive care unit. Treatment with the carbonic anhydrase inhibitor …
Carbonic anhydrase inhibitors in patients with respiratory failure …
2018年10月29日 · Background Metabolic alkalosis is common in patients with respiratory failure and may delay weaning in mechanically ventilated patients. Carbonic anhydrase inhibitors …
Population pharmacodynamic model of bicarbonate response to ...
2011年9月14日 · Introduction Acetazolamide is commonly given to chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of …
Standard vs. carbone dioxide adapted kidney replacement therapy …
2024年6月11日 · Background Current continuous kidney replacement therapy (CKRT) protocols ignore physiological renal compensation for hypercapnia. This study aimed to explore …
Management of acute metabolic acidosis in the ICU: sodium …
2021年8月31日 · The causes of acute metabolic acidosis are diverse in critically ill patients. DKA, lactic acidosis, and hyperchloremic acidosis are responsible for most cases of severe …
Impact of protocolized diuresis for de-resuscitation in the …
2020年2月28日 · Objective Administration of diuretics has been shown to assist fluid management and improve clinical outcomes in the critically ill post-shock resolution. Current guidelines have …
Causes and effects of hyperchloremic acidosis - Critical Care
2006年6月29日 · Hyperchloremia was found to have profound effects on eicosanoid release in renal tissue, leading to vasoconstriction and a reduction of the glomerular filtration rate [5]. The …
Incidence and management of metabolic acidosis with sodium …
2021年2月2日 · Background Metabolic acidosis is a major complication of critical illness. However, its current epidemiology and its treatment with sodium bicarbonate given to correct …
Practical considerations on hypoxemia and hypoxia in V-V ECMO …
2024年6月24日 · Fig. 1. Algorithm to avoid hypoxia in V-V ECMO: Algorithm for preventing and managing hypoxia on V-V ECMO at the bedside. Both, patient as well as V-V ECMO factors …