The axolotl genome and the evolution of key tissue formation ... - Nature
2018年1月24日 · Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined long-read sequencing, optical mapping and development of a new genome...
The giant axolotl genome uncovers the evolution, scaling, and ... - PNAS
2021年4月7日 · Here we describe a chromosome-scale assembly of the 32 Gb axolotl genome, an important cornerstone to study the mechanisms and evolution of gene regulation during limb development and regeneration.
A chromosome-scale assembly of the axolotl genome - PMC
This study presents a relatively cost-effective approach to scaffolding the large axolotl genome and validates the resulting assembly using both FISH and analysis of synteny conservation across vertebrates.
A chromosome-scale assembly of the axolotl genome - PubMed
The axolotl (<i>Ambystoma mexicanum</i>) provides critical models for studying regeneration, evolution, and development. However, its large genome (∼32 Gb) presents a formidable barrier to genetic analyses. Recent efforts have yielded genome assemblies consisting of thousands of unordered scaffolds ….
Complete Axolotl Genome Could Reveal the Secret of …
2019年1月24日 · While the ability to regrow an entire arm is out of reach for humans, studying the axolotl genome could reveal genetic methods of regenerating tissue that could be used in medical research.
The axolotl - Nature Methods
2023年8月8日 · The genome. In 2018, the axolotl genome was sequenced and a new era in axolotl research began. With a considerable size of 32 billion base pairs (about 10 times the size of the human genome), a...
The Axolotl’s journey to the modern molecular era - PMC
2023年3月23日 · The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci. Proceedings of the National Academy of Sciences of the United States of America, 118. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
The axolotl (Ambystoma mexicanum) provides critical models for studying regeneration, evolution, and development. However, its large genome (∼32 Gb) presents a formidable barrier to genetic analyses.
The axolotl genome and the evolution of key tissue formation
2018年2月1日 · Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined long-read sequencing, optical mapping and development of a new genome assembler (MARVEL).
(PDF) The axolotl genome and the evolution of key tissue formation ...
2018年2月1日 · Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined long-read sequencing, optical mapping and development of a new genome...