Allostatic load is "the wear and tear on the body" which accumulates as an individual is exposed to repeated or chronic stress. The term was coined by Bruce McEwen and Eliot Stellar in 1993. It represents the physiological consequences of chronic exposure to fluctuating or heightened neural or neuroendocrine response which results from repeated ...

2022年8月11日 · Allostatic load refers to the cumulative toll that chronic stress takes on your body and health. learn more about what causes allostatic load and the impact it has.

In allostatic load, it is the accumulation over time of the “wear and tear on a number of organs and tissues” that leads to physiological dysregulation and ultimately, via allostatic overload, to physical or mental illness.

Introduction: Allostatic load refers to the cumulative burden of chronic stress and life events. It involves the interaction of different physiological systems at varying degrees of activity. When environmental challenges exceed the individual ability to cope, then allostatic overload ensues.

Allostatic load is a physiological measure of the cumulative burden of stress on the body assessed by markers of physiological dysregulation. It is a multisystem construct that quantifies biological risk which leads to poor health and maladaptive trajectories.

2020年10月26日 · Allostatic overload occurs when the cumulative effects of physiological stress response lead to health problems, disease, or death.

The allostatic state represents the integrated totality of brain-body interactions. Health itself is an allostatic state of optimal anticipatory oscillation, hypothesized to relate to the state of criticality… Diseases are allostatic states of impaired anticipatory oscillations, demonstrated as rigidifications of set points across the brain ...

2024年8月18日 · At its core, allostatic load is the cumulative wear and tear on the body’s systems as they strive to maintain balance in response to ongoing stressors. To fully grasp this concept, we must first understand the relationship between allostasis and homeostasis.

Allostatic load is a multisystem construct theorized to quantify stress-induced biological risk. Differences in allostatic load may reflect differences in stress exposure and thus provide a mechanistic link to understanding health disparities.

1998年1月15日 · The meaning of ALLOSTATIC LOAD is the cumulative adverse effect on the body when allostasis occurs too frequently (as when the body is subjected to repeated stressors) or is inadequate. How to use allostatic load in a sentence.