Short-course treatment regimens, like 3HP and 4R, are effective, safe, and have higher completion rates than longer 6 to 9 months of isoniazid monotherapy (6H/9H). Shorter, rifamycin-based treatment regimens generally have a lower risk of hepatotoxicity than 6H and 9H.

2024年3月8日 · Health care providers can use this checklist with patients who are prescribed the 12-dose regimen, also known as 3HP, to treat latent TB infection. Patients can keep track of treatment schedules, medication intake, and doctor/clinic contact information.

Treatment regimens for latent TB infection (LTBI) use isoniazid (INH), rifapentine (RPT), or rifampin (RIF). CDC and the National Tuberculosis Controllers Association preferentially recommend short-course, rifamycin-based, 3- or 4-month latent TB infection treatment regimens over 6- or 9-month isoniazid monotherapy.

What is the 12-dose isoniazid/rifapentine regimen (aka “3HP”)? Who is not recommended for treatment with 3HP? The 3HP regimen consists of 12 once-weekly doses of isoniazid (H) and rifapentine (Priftin®) (P). It provides a safe and efective treatment for LTBI.

2020年4月1日 · 3HP is a short-course Tuberculosis Preventive Treatment (TPT) regimen which is endorsed by the WHO. It combines high dose Isoniazid (H) and high dose rifapentine (P) once weekly for three months. 3HP is associated with significantly lower hepatotoxicity and higher rates of treatment completion than isoniazid preventive treatment.

Quickly identify and answer key questions when considering whether to start a patient on the 3HP regimen; Assess the appropriateness of self-administered therapy of 3HP for each individual patient; Ensure that the correct drugs for the 3HP regimen …

What is 3HP? 3HP is a short-course TPT regimen that combines two antibiotics used to treat TB—isoniazid and rifapentine—taken only once a week for 12 weeks. f Components: 900mg isoniazid(H) + 900mg rifapentine(P), currently given as a Fixed-dose Combination (FDC) (3 tablets, 300mg isoniazid, 300mg rifapentine, weekly) or as separate tablets

What is the 12-dose INH/rifapentine regimen (3HP)? It is 12 once-weekly doses of INH and rifapentine for the treatment of LTBI. The regimen is referred to as “3HP.”

2020年4月3日 · 3HP is a short-course TB preventive treatment (TPT) regimen taken once weekly for 12 weeks which is endorsed by the WHO1. It combines high dose isoniazid (H) and high dose rifapentine (P).

rifapentine (3HP), previously recommended for most persons aged 12 years and older, have been expanded to include: • Children ages 2 - 11 • People living with HIV taking antiretroviral treatment (with acceptable drug-drug interactions with rifapentine) • Clinicians can now prescribe the 12-dose regimen to patients as self-administered