Ascites is defined as the pathologic accumulation of fluid in the peritoneal cavity. It is the most common complication of cirrhosis, which is the most common cause of ascites in the United States, accounting for approximately 85 percent of cases.

Ascites can cause or is associated with a number of complications including spontaneous bacterial peritonitis, hepato-hydrothorax and hepatorenal syndrome. Ascites itself, and these associated complications are a significant cause of morbidity and mortality in cirrhotic patients.

2023年8月8日 · Ascites is the pathologic accumulation of fluid within the peritoneal cavity. It is the most common complication of cirrhosis and occurs in about 50% of patient with decompensated cirrhosis in 10 years. The development of ascites denotes the transition from compensated to decompensated cirrhosis.

Ascites occurs in more than 50% of patients with cirrhosis, worsens the course of the disease, and reduces survival substantially. Portal hypertension, splanchnic vasodilatation, liver insufficiency, and cardiovascular dysfunction are major pathophysiological hallmarks.

2024年6月2日 · In this article, we shall cover the causes and pathophysiology of ascites. There are a number of disorders of conditions that can cause ascites but the most common of them are malignant diseases, liver cirrhosis, and heart failure.

2023年5月30日 · Three theories of ascites formation have been proposed: underfilling, overflow, and peripheral arterial vasodilation. The underfilling theory suggests that the primary abnormality is...

2009年6月1日 · Ascites occurs in more than 50% of patients with cirrhosis, worsens the course of the disease, and reduces survival substantially. Portal hypertension, splanchnic vasodilatation, liver...

2008年9月20日 · The pathophysiology behind the formation and perpetuation of ascites is complex. Three major factors are involved in the pathogenesis: portal and sinusoidal hypertension, arterial vasodilatation, and neurohumoral activation, all leading to sodium and water retention [ 9 , 10 ].

4 天之前 · Ascites is characterised by an accumulation of fluid in the peritoneal cavity. While it is commonly associated with liver cirrhosis, it may also result from malignancy, cardiac failure or renal disease. This clinical review explores the pathogenesis, clinical presentation, diagnostic approaches and management strategies for ascites, emphasising its multifaceted nature and clinical implications ...

In this review, we examine the mechanisms that contribute to the development of ascites in patients with cirrhosis and portal hypertension. Disturbance of the circulatory system frequently occurs in patients with cirrhosis. Cardiac index and plasma volume increase whereas mean arterial blood pressure and systemic vascular resistance decrease.