2023年5月17日 · Myocardial fibrosis is a condition that causes scar tissue to build up in your heart. It’s most common after a heart attack, but it can occur at other times as well....

Cardiac fibrosis commonly refers to the excess deposition of extracellular matrix in the cardiac muscle, but the term may also refer to an abnormal thickening of the heart valves due to inappropriate proliferation of cardiac fibroblasts. [1]

2024年2月16日 · Myocardial fibrosis is a condition that involves the buildup of scar tissue in the myocardium, which is the heart muscle. Anything that causes damage to the heart can lead to scar tissue. Heart attacks are the most common cause of myocardial fibrosis. Both sudden heart injury and chronic heart injury due to disease can cause scar tissue to form.

2016年3月18日 · Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease. Cardiac fibroblasts comprise an essential cell type in the heart that is responsible fo...

2019年6月1日 · In this review, we present an overview of what is known about cardiac fibrosis including the role of cardiac cells and extracellular matrix in this disease. We will further summarize current diagnostic tools and highlight pre-clinical or clinical therapeutic strategies to address cardiac fibrosis. 1. Introduction.

2021年5月25日 · Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of extracellular matrix proteins, is a common pathophysiologic companion of many different myocardial conditions. Fibrosis may reflect activation of reparative or maladaptive processes.

2021年2月10日 · Diffuse myocardial fibrosis is characterized by excessive diffuse interstitial and perivascular deposition of highly crosslinked collagen fibres (type I collagen) and other components of the...

Myocardial fibrosis is a pathological condition characterized by the excessive deposition of extracellular matrix (ECM) proteins, particularly collagen, within the myocardium. This process leads to the stifening and scarring of heart tissue, significantly impacting cardiac function.

In this review, we discuss the pathophysiology of myocardial fibrosis, review the applications of CMR in the non-invasive detection of myocardial fibrosis and provide an overview of common pathologies in which fibrosis imaging may be of clinical utility.

2025年2月7日 · Cardiac fibrosis is characterized by an excessive deposition of extracellular matrix, which disrupts the myocardial architecture and impairs the heart microvasculature, leading to cardiac dysfunction.