Actin - Wikipedia
Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 μM; its mass …
Actin Polymerization - an overview | ScienceDirect Topics
Actin polymerization provides driving force to aid several types of processes that involve pulling the plasma membrane into the cell, including phagocytosis, cellular entry of large viruses, and endocytosis. In endocytosis, actin polymerization is especially important under conditions of high membrane tension or high turgor pressure.
Structure and Organization of Actin Filaments
The assembly of actin filaments can be studied in vitro by regulation of the ionic strength of actin solutions. In solutions of low ionic strength, actin filaments depolymerize to monomers. Actin then polymerizes spontaneously if the ionic strength is increased to physiological levels.
Actin Structure and Function: What We Still Do Not Understand
Actin is found in two main states: G-actin (G for globular) is the monomeric form (Fig. 1), whereas F-actin (F for filamentous) is the helical polymer (Fig. 2).
Actin: Anatomy and function - Kenhub
2023年10月30日 — Actin exists in two forms: G-actin (monomeric globular actin) and F-actin (polymeric fibrous actin). G-actin is responsible for the formation of the actin filament, while F-actin forms the cytoskeleton and contractile apparatus of muscle cells.
Actin Polymerization and ATP Hydrolysis | Science - AAAS
Polymeric F-actin is formed by reversible noncovalent self-association of monomeric G-actin. To understand the dynamics of microfilament systems in cells, the dynamics of polymerization of pure actin must be understood. The following model has emerged from recent work.
Actin polymerisation and crosslinking drive left-right ... - Nature
2023年2月11日 — In this work, the authors identify regulators of actin filament assembly involved in chiral organisation of the actin cytoskeleton in single cells and chiral alignment of cells in groups.
Actin, a Central Player in Cell Shape and Movement | Science
2009年11月27日 — The protein actin forms filaments that provide cells with mechanical support and driving forces for movement. Actin contributes to biological processes such as sensing environmental forces, internalizing membrane vesicles, …
Catching actin proteins in action - Nature
26 October 2022. Catching actin proteins in action. Two groups have visualized actin — the protein polymer that gives cells their shape — at high resolution. The structures provide in-depth...
Biochemical and mechanical regulation of actin dynamics
2022年8月2日 — Polymerization of actin filaments against membranes produces force for numerous cellular processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle dynamics.