BACKGROUND: Cardiomyocytes in the adult human heart show a regenerative capacity, with an annual renewal rate of ≈0.5%. Whether this regenerative capacity of human cardiomyocytes is employed in heart ...
Introduction: Our previous studies have shown that sustained activation of the DNA damage response (DDR) in cardiomyocytes leads to p53/p21 activation and cardiac dysfunction. Although the DDR ...
A research team reported recently that heart muscle cells grown from induced pluripotent stem cells can integrate into the hearts of monkeys with a state of pressure overload.
“Lab studies showed these trace-level cytokines had a direct effect on the functionality of cardiomyocytes, the cells of the heart responsible for its pump function.” Professor Short noted that these ...