Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, ...

Bicuspid aortic valve disease, where the aortic valve has two leaflets instead of the normal three, is the most common congenital heart defect, affecting up to 2% of the population.

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There are three main forms of aortic valve disease: congenital abnormalities, such as a bicuspid valve that leads to premature calcification; calcification of the normal trileaflet valve ...

Contribution of rare chromosome 22q11.2 copy number variants to non-syndromic bicuspid aortic valve. Heart , 2024; heartjnl-2024-324669 DOI: 10.1136/heartjnl-2024-324669 Cite This Page : ...

The Edwards Sapien valve consists of a balloon-expandable stent of stainless steel surrounded by a polyester fabric sealing cuff in which a trileaflet ... inside the native aortic annulus and ...

Objective After transcatheter aortic valve implantation (TAVI), the optimal regimen of anticoagulant therapy in patients with an additional indication for oral anticoagulation remains a matter of ...

Based on the results from the MATTERHORN (A Multicenter, Randomized, Controlled Study to Assess Mitral Valve Reconstruction for Advanced Insufficiency of Functional or Ischemic Origin), transcatheter ...

THE human aortic valve consists of three cusps made of relatively inelastic, muscle-free material about 0.15 mm thick. It opens and shuts about once a second, and withstands a pressure difference ...

Indication for treatment of non-critical VAS was Doppler mean gradient >50 mm Hg. Main outcome measures Short-term and long-term survival, aortic valve reinterventions need of valve replacements, risk ...

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This time, doctors performed thorough scans, and transferred her to the National Heart Centre Singapore (NHCS). She was diagnosed with severe aortic stenosis. This is a degenerative heart condition in ...